ID   PAIR1_ORYSJ             Reviewed;         492 AA.
AC   Q75RY2; Q10SZ9; Q8H7T8;
DT   21-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Protein PAIR1;
DE   AltName: Full=Protein HOMOLOGOUS PAIRING ABERRATION IN RICE MEIOSIS 1;
GN   Name=PAIR1; OrderedLocusNames=Os03g0106300, LOC_Os03g01590;
GN   ORFNames=OSJNBa0009C08.13;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, TISSUE
RP   SPECIFICITY, AND DEVELOPMENTAL STAGE.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15031413; DOI=10.1105/tpc.020701;
RA   Nonomura K., Nakano M., Fukuda T., Eiguchi M., Miyao A., Hirochika H.,
RA   Kurata N.;
RT   "The novel gene HOMOLOGOUS PAIRING ABERRATION IN RICE MEIOSIS1 of rice
RT   encodes a putative coiled-coil protein required for homologous chromosome
RT   pairing in meiosis.";
RL   Plant Cell 16:1008-1020(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16109971; DOI=10.1101/gr.3869505;
RG   The rice chromosome 3 sequencing consortium;
RA   Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA   Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA   Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA   Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA   Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA   Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA   Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA   Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA   Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA   Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA   O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA   Jin W., Lee H.R., Jiang J., Jackson S.;
RT   "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT   and diverged grass species.";
RL   Genome Res. 15:1284-1291(2005).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [5]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [6]
RP   INTERACTION WITH CRC1.
RX   PubMed=23943860; DOI=10.1105/tpc.113.113175;
RA   Miao C., Tang D., Zhang H., Wang M., Li Y., Tang S., Yu H., Gu M.,
RA   Cheng Z.;
RT   "Central region component1, a novel synaptonemal complex component, is
RT   essential for meiotic recombination initiation in rice.";
RL   Plant Cell 25:2998-3009(2013).
CC   -!- FUNCTION: Involved in spore formation. Plays an essential role in the
CC       establishment of homologous chromosome pairing in early meiosis.
CC       {ECO:0000269|PubMed:15031413}.
CC   -!- SUBUNIT: Interacts with CRC1. {ECO:0000269|PubMed:23943860}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15031413}.
CC   -!- TISSUE SPECIFICITY: Expressed in reproductive organs, but not in
CC       vegetative organs. {ECO:0000269|PubMed:15031413}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in early stages of flower development.
CC       Highest expression is observed when the panicle growth reaches 30
CC       millimeters. {ECO:0000269|PubMed:15031413}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAN60485.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AB158462; BAD15032.1; -; mRNA.
DR   EMBL; AC107224; AAN60485.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; DP000009; ABF93533.1; -; Genomic_DNA.
DR   EMBL; AP008209; BAF10598.1; -; Genomic_DNA.
DR   EMBL; AP014959; BAS81870.1; -; Genomic_DNA.
DR   RefSeq; XP_015632198.1; XM_015776712.1.
DR   AlphaFoldDB; Q75RY2; -.
DR   SMR; Q75RY2; -.
DR   STRING; 4530.OS03T0106300-00; -.
DR   PaxDb; Q75RY2; -.
DR   PRIDE; Q75RY2; -.
DR   EnsemblPlants; Os03t0106300-01; Os03t0106300-01; Os03g0106300.
DR   GeneID; 4331321; -.
DR   Gramene; Os03t0106300-01; Os03t0106300-01; Os03g0106300.
DR   KEGG; osa:4331321; -.
DR   eggNOG; ENOG502QT68; Eukaryota.
DR   HOGENOM; CLU_030530_1_0_1; -.
DR   InParanoid; Q75RY2; -.
DR   OMA; NSASCVR; -.
DR   OrthoDB; 914162at2759; -.
DR   Proteomes; UP000000763; Chromosome 3.
DR   Proteomes; UP000059680; Chromosome 3.
DR   Genevisible; Q75RY2; OS.
DR   GO; GO:0005634; C:nucleus; IDA:Gramene.
DR   GO; GO:0070192; P:chromosome organization involved in meiotic cell cycle; IEA:InterPro.
DR   GO; GO:0009553; P:embryo sac development; IBA:GO_Central.
DR   GO; GO:0009554; P:megasporogenesis; IDA:Gramene.
DR   GO; GO:0042138; P:meiotic DNA double-strand break formation; IBA:GO_Central.
DR   GO; GO:0009556; P:microsporogenesis; IDA:Gramene.
DR   InterPro; IPR034546; PAIR1.
DR   PANTHER; PTHR37695; PTHR37695; 4.
PE   1: Evidence at protein level;
KW   Coiled coil; Meiosis; Nucleus; Reference proteome.
FT   CHAIN           1..492
FT                   /note="Protein PAIR1"
FT                   /id="PRO_0000058181"
FT   COILED          166..186
FT                   /evidence="ECO:0000255"
FT   MOTIF           479..483
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   492 AA;  53631 MW;  9AFC3C54C3CBA208 CRC64;
     MKLKMNKACD IASISVLPPR RTGGSSGASA SGSVAVAVAS QPRSQPLSQS QQSFSQGASA
     SLLHSQSQFS QVSLDDNLLT LLPSPTRDQR FGLHDDSSKR MSSLPASSAS CAREESQLQL
     AKLPSNPVHR WNPSIADTRS GQVTNEDVER KFQHLASSVH KMGMVVDSVQ SDVMQLNRAM
     KEASLDSGSI RQKIAVLESS LQQILKGQDD LKALFGSSTK HNPDQTSVLN SLGSKLNEIS
     STLATLQTQM QARQLQGDQT TVLNSNASKS NEISSTLATL QTQMQADIRQ LRCDVFRVFT
     KEMEGVVRAI RSVNSRPAAM QMMADQSYQV PVSNGWTQIN QTPVAAGRSP MNRAPVAAGR
     SRMNQLPETK VLSAHLVYPA KVTDLKPKVE QGKVKAAPQK PFASSYYRVA PKQEEVAIRK
     VNIQVPAKKA PVSIIIESDD DSEGRASCVI LKTETGSKEW KVTKQGTEEG LEILRRARKR
     RRREMQSIVL AS