PAIR3_ORYSJ
ID PAIR3_ORYSJ Reviewed; 844 AA.
AC B9G5N1; Q0IXX0; Q7XEV4; Q948J1;
DT 18-JAN-2017, integrated into UniProtKB/Swiss-Prot.
DT 24-MAR-2009, sequence version 1.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=Meiosis-specific protein PAIR3 {ECO:0000305};
DE AltName: Full=Protein HOMOLOGOUS PAIRING ABERRATION IN RICE MEIOSIS 3 {ECO:0000303|PubMed:19392701};
GN Name=PAIR3 {ECO:0000303|PubMed:19392701};
GN OrderedLocusNames=Os10g0405500 {ECO:0000312|EMBL:BAT10769.1},
GN LOC_Os10g26560 {ECO:0000312|EMBL:AAP53684.1};
GN ORFNames=OsJ_31462 {ECO:0000312|EMBL:EEE50928.1},
GN OSJNBa0060A14.5 {ECO:0000312|EMBL:AAK98671.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], FUNCTION, TISSUE SPECIFICITY, AND
RP DISRUPTION PHENOTYPE.
RX PubMed=19392701; DOI=10.1111/j.1365-313x.2009.03870.x;
RA Yuan W., Li X., Chang Y., Wen R., Chen G., Zhang Q., Wu C.;
RT "Mutation of the rice gene PAIR3 results in lack of bivalent formation in
RT meiosis.";
RL Plant J. 59:303-315(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12791992; DOI=10.1126/science.1083523;
RA Yu Y., Rambo T., Currie J., Saski C., Kim H.-R., Collura K., Thompson S.,
RA Simmons J., Yang T.-J., Nah G., Patel A.J., Thurmond S., Henry D.,
RA Oates R., Palmer M., Pries G., Gibson J., Anderson H., Paradkar M.,
RA Crane L., Dale J., Carver M.B., Wood T., Frisch D., Engler F.,
RA Soderlund C., Palmer L.E., Teytelman L., Nascimento L., De la Bastide M.,
RA Spiegel L., Ware D., O'Shaughnessy A., Dike S., Dedhia N., Preston R.,
RA Huang E., Ferraro K., Kuit K., Miller B., Zutavern T., Katzenberger F.,
RA Muller S., Balija V., Martienssen R.A., Stein L., Minx P., Johnson D.,
RA Cordum H., Mardis E., Cheng Z., Jiang J., Wilson R., McCombie W.R.,
RA Wing R.A., Yuan Q., Ouyang S., Liu J., Jones K.M., Gansberger K.,
RA Moffat K., Hill J., Tsitrin T., Overton L., Bera J., Kim M., Jin S.,
RA Tallon L., Ciecko A., Pai G., Van Aken S., Utterback T., Reidmuller S.,
RA Bormann J., Feldblyum T., Hsiao J., Zismann V., Blunt S., de Vazeille A.R.,
RA Shaffer T., Koo H., Suh B., Yang Q., Haas B., Peterson J., Pertea M.,
RA Volfovsky N., Wortman J., White O., Salzberg S.L., Fraser C.M., Buell C.R.,
RA Messing J., Song R., Fuks G., Llaca V., Kovchak S., Young S., Bowers J.E.,
RA Paterson A.H., Johns M.A., Mao L., Pan H., Dean R.A.;
RT "In-depth view of structure, activity, and evolution of rice chromosome
RT 10.";
RL Science 300:1566-1569(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=21119003; DOI=10.1091/mbc.e10-08-0667;
RA Wang K., Wang M., Tang D., Shen Y., Qin B., Li M., Cheng Z.;
RT "PAIR3, an axis-associated protein, is essential for the recruitment of
RT recombination elements onto meiotic chromosomes in rice.";
RL Mol. Biol. Cell 22:12-19(2011).
RN [8]
RP SUBCELLULAR LOCATION.
RX PubMed=27436711; DOI=10.1105/tpc.16.00108;
RA He Y., Wang C., Higgins J.D., Yu J., Zong J., Lu P., Zhang D., Liang W.;
RT "MEIOTIC F-BOX is essential for male meiotic DNA double-strand break repair
RT in rice.";
RL Plant Cell 28:1879-1893(2016).
CC -!- FUNCTION: Plays a crucial role in homologous chromosome pairing and
CC synapsis in meiosis. Does not seem required for cytokinesis
CC (PubMed:19392701). Is essential for meiotic bouquet formation,
CC homologous chromosome pairing and normal recombination, and
CC synaptonemal complex (SC) assembly. Required for the proper association
CC of PAIR2 with chromosomes (PubMed:21119003).
CC {ECO:0000269|PubMed:19392701, ECO:0000269|PubMed:21119003}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000269|PubMed:21119003,
CC ECO:0000269|PubMed:27436711}. Nucleus {ECO:0000269|PubMed:21119003}.
CC Note=During interphase-early leptotene, distributed as numerous
CC punctuate foci throughout the chromatin. Associates with chromosomal
CC axes at leptotene, zygotene and pachytene (PubMed:21119003). Associates
CC with chromosomal axes at zygotene (PubMed:27436711).
CC {ECO:0000269|PubMed:21119003, ECO:0000269|PubMed:27436711}.
CC -!- TISSUE SPECIFICITY: Expressed in pollen mother cells and the ovule
CC tissues during meiosis. {ECO:0000269|PubMed:19392701}.
CC -!- DISRUPTION PHENOTYPE: Sterility in both male and female gametes.
CC {ECO:0000269|PubMed:19392701}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAK98671.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAP53684.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAF26473.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; FJ449711; ACN49116.1; -; Genomic_DNA.
DR EMBL; FJ449712; ACN49117.1; -; mRNA.
DR EMBL; AC021893; AAK98671.1; ALT_SEQ; Genomic_DNA.
DR EMBL; DP000086; AAP53684.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008216; BAF26473.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014966; BAT10769.1; -; Genomic_DNA.
DR EMBL; CM000147; EEE50928.1; -; Genomic_DNA.
DR RefSeq; XP_015614883.1; XM_015759397.1.
DR AlphaFoldDB; B9G5N1; -.
DR SMR; B9G5N1; -.
DR STRING; 4530.OS10T0405500-01; -.
DR PaxDb; B9G5N1; -.
DR PRIDE; B9G5N1; -.
DR EnsemblPlants; Os10t0405500-01; Os10t0405500-01; Os10g0405500.
DR GeneID; 4348581; -.
DR Gramene; Os10t0405500-01; Os10t0405500-01; Os10g0405500.
DR KEGG; osa:4348581; -.
DR eggNOG; ENOG502R6IY; Eukaryota.
DR HOGENOM; CLU_011891_0_0_1; -.
DR OMA; STHQDKS; -.
DR OrthoDB; 233900at2759; -.
DR Proteomes; UP000000763; Chromosome 10.
DR Proteomes; UP000007752; Chromosome 10.
DR Proteomes; UP000059680; Chromosome 10.
DR GO; GO:0005694; C:chromosome; IDA:UniProtKB.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0007129; P:homologous chromosome pairing at meiosis; IMP:UniProtKB.
DR InterPro; IPR037731; ASY3-like.
DR PANTHER; PTHR36027; PTHR36027; 1.
PE 2: Evidence at transcript level;
KW Chromosome; Coiled coil; Meiosis; Nucleus; Reference proteome.
FT CHAIN 1..844
FT /note="Meiosis-specific protein PAIR3"
FT /id="PRO_0000438700"
FT REGION 41..389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 418..506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 532..604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 731..765
FT /evidence="ECO:0000255"
FT COMPBIAS 41..68
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..123
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..285
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 301..318
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 320..360
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..378
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 418..445
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 452..470
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 541..556
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..646
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 844 AA; 93298 MW; DDA0F2BE7A3E25B9 CRC64;
MEVELTNIQK ATSSDYWSLA SNQYPCGKFP KVSVGVTIPR TSSVSRGRDA ASTAAFEKNL
SQGTDGRSRP PKMDNASLQV SPEAANHGGS AKEVPKPVPA KVSVSQPDDN AIEQTGTFSF
GTRREQDSHL DQLDRPPLVS SQGKRQVESA DKNKPNSEML RMKLWEILGG TSQNKEAVAS
PNPEDIETPC QPKSQIANGP SSGRQKVFTS PVPYNIKTPA QFNSQTANKP SSDPIESDSD
SPQVVEVRPI TRSLGRKKEP TGSTHQDKSG SAKKPLSTHR STPKQKILDN VFAFNDKCTP
KTVGKSANGE SGSLRNLRSL SRRAKVEPKK AHCSDRISHK TTQDDMERKV PSKYIPSEKK
GEKTNSFSSL SRTGKTAESC SRSPKRERRV NTMANVGARK MQLSENLLVK TLNDGEHKLS
SPQLTSFKSK GKCSSISPQQ KENDNTHIPE ASDRTAARNS FNSTPSPAAN PSPVLRKYSW
EHDENPAING KSGQKDASPL ADRFSDMPDD FASPTFAANI KISPHRSKML DDDLFSSKYP
KGVNRSRSTS FTSDPESEPL DKMEKTNELP GSESPNSQEE RQNRKQPHLS PLSPIESEGA
QISIPSFRKG YKSHKWLSDV DSPDKSSIEH LGRKSHLKEG RKGKRQLTSP THFATSGTQE
TMSDKEPEKV PENYLTRAFD QLVVVLGRFQ TKIKSETRNK SSKILAATGE IIRQHLEGVE
GQMQADVDKL VNAGKSKRKR LESTFEEQQE KLRILHEKFK EEVNQQLLGC KNSVEDFEAY
HAELKGVADK QKASHKKLLQ NAEKTVGAQL SDAETKIAEV QKRARKRMKG LKFVLKELIA
ETAE
