ID   PALC_YARLI              Reviewed;         441 AA.
AC   Q6C1E4;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=pH-response regulator protein palC;
GN   OrderedLocusNames=YALI0F17028g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for the proteolytic cleavage of the transcription
CC       factor RIM101 in response to alkaline ambient pH. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the palC family. {ECO:0000305}.
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DR   EMBL; CR382132; CAG78327.1; -; Genomic_DNA.
DR   RefSeq; XP_505518.1; XM_505518.1.
DR   AlphaFoldDB; Q6C1E4; -.
DR   SMR; Q6C1E4; -.
DR   EnsemblFungi; CAG78327; CAG78327; YALI0_F17028g.
DR   GeneID; 2907826; -.
DR   KEGG; yli:YALI0F17028g; -.
DR   VEuPathDB; FungiDB:YALI0_F17028g; -.
DR   HOGENOM; CLU_027723_0_0_1; -.
DR   InParanoid; Q6C1E4; -.
DR   OMA; ANQYVAR; -.
DR   Proteomes; UP000001300; Chromosome F.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0071467; P:cellular response to pH; IBA:GO_Central.
DR   Gene3D; 1.25.40.280; -; 1.
DR   InterPro; IPR004328; BRO1_dom.
DR   InterPro; IPR038499; BRO1_sf.
DR   InterPro; IPR037505; pH-resp_palC.
DR   PANTHER; PTHR40463; PTHR40463; 1.
DR   Pfam; PF03097; BRO1; 1.
DR   SMART; SM01041; BRO1; 1.
DR   PROSITE; PS51180; BRO1; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..441
FT                   /note="pH-response regulator protein palC"
FT                   /id="PRO_0000218890"
FT   DOMAIN          3..352
FT                   /note="BRO1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00526"
FT   REGION          278..304
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          414..441
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        287..304
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   441 AA;  48451 MW;  350253B453B978B0 CRC64;
     MSISYTGQLP TTSPLSLTQL ITSDRYQQVI ENADAARARV REQLKHAKKT GATEANGDIM
     PVIKALEEYM PHITSIVDNE GVFRFTSQII TCWRLPFQSQ SSMANKTPLH GLSFEYIMVL
     FTYALALATL ANQYVARDKE DRWKHASAYI SKARGVVDYL RQCRSFQIIC NEPPASVPRD
     LSSATMSALS HMLCGASHML ILYKCDAETY LDGGAPSAGA NSGGFSSSLL LRTAIFARDQ
     FETASALLGE PVSKRKLVTS LVKEKSSKFS LSKKLHLRKD DGSPSLAPVS SFESNRDLSS
     TSSGTLDSLL SWLSRARGVA EGFVFKHMAI QAYENNQIGK AVGAAYAAIL QLEDVKIPQK
     SALYIPVTHL KETLNRHHAD YKADNDRLSF EPVPSPSELA QEWPSGRQVI SAQKWTPQTS
     LDLGEDTSSS APKYSGQGSY Y