PALD_CHICK
ID PALD_CHICK Reviewed; 868 AA.
AC Q8JHZ8; Q5ZKE4;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2007, sequence version 2.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=Paladin;
GN Name=PALD1; Synonyms=PALD; ORFNames=RCJMB04_11g7;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Jordan J.D., Iyengar R.;
RT "Gao/i targeting of direct interactors for degradation by the ubiquitin-
RT dependent proteasome system.";
RL Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the paladin family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAN03688.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=CAG31799.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AF411975; AAN03688.1; ALT_INIT; mRNA.
DR EMBL; AJ720140; CAG31799.1; ALT_INIT; mRNA.
DR RefSeq; NP_989440.2; NM_204109.2.
DR AlphaFoldDB; Q8JHZ8; -.
DR STRING; 9031.ENSGALP00000007093; -.
DR PaxDb; Q8JHZ8; -.
DR GeneID; 373898; -.
DR KEGG; gga:373898; -.
DR CTD; 27143; -.
DR VEuPathDB; HostDB:geneid_373898; -.
DR eggNOG; ENOG502QQ90; Eukaryota.
DR InParanoid; Q8JHZ8; -.
DR OrthoDB; 197637at2759; -.
DR PhylomeDB; Q8JHZ8; -.
DR PRO; PR:Q8JHZ8; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IBA:GO_Central.
DR Gene3D; 3.90.190.10; -; 2.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR SUPFAM; SSF52799; SSF52799; 2.
PE 2: Evidence at transcript level;
KW Cytoplasm; Lipoprotein; Myristate; Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000255"
FT CHAIN 2..868
FT /note="Paladin"
FT /id="PRO_0000286132"
FT LIPID 2
FT /note="N-myristoyl glycine"
FT /evidence="ECO:0000255"
FT CONFLICT 763
FT /note="T -> A (in Ref. 2; CAG31799)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 868 AA; 99632 MW; 8C602A7F32CBD233 CRC64;
MGTTASTAQQ TVSASAFESV HGIGTMEDQR SLSIHSFQTL GLHNSKAKSI ITNKVAPVVI
TYNCREEFQI HDDLLKANYT VGRISDATLE HYLVQGKYFM VRDVYSKLDV LNTTASCGAP
NFRQAKGGYA VFGMGQPSLG GFKLVLQKLQ REGHKECVFF CVREEPVLFL RVESDFVPYT
PRGKENLHEN LHSLRRGLRV EDLELTIRKE IHDFAQLSEG VYYVYNDIER FRDEPHTVRV
QGEEDIHVTE EVYRRPIFLL PTYRYHRLPL PVDGAPLEEQ FDAFICFLRE SSGLLLRDPS
RPPPALLFSC QTGVGRTNLA MALGTLILHH HRGAAPKPDP PHPAKMPPRA RFRVIQSFIE
MVPKGQQMVE EVDSVIASCS EMHDMKEAIY ESKKKLEGIG EDYQIQGNST KEYFLQRTLQ
SLERYFYLIA FNYYLHEQYP LGFALSFSRW MCRHPELYRL QAIMNSSELT ITGDLITKGT
RVLVVDERFC PDVLSTVKEM SVANFRRVPK MPIYGTAQPS SKALGSVLRY LTDAKRKHSR
ILWVSLREEV VLEGNEQIYT LREPGSLDQL IPVPVSTPEQ LEKLESTLKG DLLKSQKWLE
VYLEAEKQMK MFKSCLTTQE IFNQHKSTCQ GLTYRRIPIP DFCAPKEQDF DRLLEAMKSA
LAEDSQTAFV FNCASGRGRT TTAMVIAVLT LWHFNGIPEM SEEEIVSVPD AKYTKGEFEV
VMKVVQLLPD GHRMKKEVDM ALDTVSETMT PMHYHLREII ICTYRQGRSG KDEQERRLLR
LRSLQYLERY IYLILFNSYL HLEKKDSWQR PFSLWMREVA AVAGVYEVLD GLGFPELEQL
EDEEPLRKLR GRWRAQSGAG WPSRGDLV