ID   PALD_XENTR              Reviewed;         872 AA.
AC   Q6DIR8;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Paladin;
GN   Name=pald1; Synonyms=pald; ORFNames=TGas002h03.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Gastrula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the paladin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR855717; CAJ82510.1; -; mRNA.
DR   EMBL; BC075467; AAH75467.1; -; mRNA.
DR   RefSeq; NP_001006726.1; NM_001006725.1.
DR   AlphaFoldDB; Q6DIR8; -.
DR   STRING; 8364.ENSXETP00000051230; -.
DR   PaxDb; Q6DIR8; -.
DR   PRIDE; Q6DIR8; -.
DR   DNASU; 448380; -.
DR   GeneID; 448380; -.
DR   KEGG; xtr:448380; -.
DR   CTD; 27143; -.
DR   Xenbase; XB-GENE-5740535; pald1.
DR   eggNOG; ENOG502QQ90; Eukaryota.
DR   InParanoid; Q6DIR8; -.
DR   OrthoDB; 197637at2759; -.
DR   Proteomes; UP000008143; Chromosome 7.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IBA:GO_Central.
DR   Gene3D; 3.90.190.10; -; 2.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   SUPFAM; SSF52799; SSF52799; 2.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasm; Lipoprotein; Myristate; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000255"
FT   CHAIN           2..872
FT                   /note="Paladin"
FT                   /id="PRO_0000286134"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          186..210
FT                   /evidence="ECO:0000255"
FT   LIPID           2
FT                   /note="N-myristoyl glycine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   872 AA;  100259 MW;  D4695248339E18A6 CRC64;
     MGTTASAAQQ VPSTVPSSEN VQGNGSGSSN VEDRNSLSTQ SFQNVSIHNK AKSIITNKVA
     PVVITYNCKE EFQIHDDLLK ANYSVGRISE TMPEHYLVQG KYFMVHDVYS KLDVLNTTSS
     CGAPNFRQAR GGYEVYGMGQ PSLNGFKQVL QKLQSNGHKE CVFFCVREEP VLFLKLEDDF
     VPYTPRRKEN LHENLHDLEK GLRAENLELA IRKELHDFAQ LSGNSYYVYN DIEHFKDEPH
     SIIIHCEEDI HVTEEVYNRP VFLLPAYRYH RLPLPMDGAP LETQFDAFVN ILRENPSLLL
     LHDANHPPPA LLFSCQTGVG RTNLAMILGT LVLYHRKGAC EKQTISQDTN VLPKQRFQVI
     QNFINMVPNG EAIVDEVDKA IELCSEMHDI KAALYECKKK LEGIGEGYQI QGSSTKEYFL
     KGTLHSLERY FYLITFNYYL HEQYPLAFAL SFSKWMCTQP WIYRLQASLN LSELTLSGEL
     ITKGTRVLVL DDRFSPDVLS TLKEMNVANF RRVPKMPVYG TAQPSLKATG SVLSYLTDAK
     RKYSNILWVN LREDVILEAN EQIFTPREPD NLEQQIAVPA ASPEQLEKLE ATVANHVLTS
     QKWLEVYLEQ EKQMKMFKTC RTMQEIFNQH RSAYPGLVYR RIPIPDFCAP REQDFDMLLQ
     SMKSMLAEDS SAAFVFNCHG GKGRTTTAMV IAVLTLWHFN SIPEITEDEI VSVPDAKYTK
     GEFEVVMKIV QLLPDGHKIK KEVDMALDSI SETMTPMHYH LREIIICTYR QVKTAKNSKE
     MRLLQLRSLQ YLERYIYLIL FNAYLHLEKK DTWQRPFSTW MYEVASKAGV YEVLNQLGFS
     EFENAEEQPL CRLRYRWQQQ NTNLLPFRGE FI