ID   PALF_CANGA              Reviewed;         649 AA.
AC   Q6FVR8;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=pH-response regulator protein palF/RIM8;
GN   Name=RIM8; OrderedLocusNames=CAGL0D06204g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for the proteolytic cleavage of the transcription
CC       factor RIM101 in response to alkaline ambient pH. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the arrestin family. PalF/RIM8 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; CR380950; CAG58587.1; -; Genomic_DNA.
DR   RefSeq; XP_445676.1; XM_445676.1.
DR   AlphaFoldDB; Q6FVR8; -.
DR   STRING; 5478.XP_445676.1; -.
DR   EnsemblFungi; CAG58587; CAG58587; CAGL0D06204g.
DR   GeneID; 2887003; -.
DR   KEGG; cgr:CAGL0D06204g; -.
DR   CGD; CAL0128259; CAGL0D06204g.
DR   VEuPathDB; FungiDB:CAGL0D06204g; -.
DR   eggNOG; ENOG502QTQN; Eukaryota.
DR   HOGENOM; CLU_006001_1_0_1; -.
DR   InParanoid; Q6FVR8; -.
DR   OMA; GMSIEIV; -.
DR   Proteomes; UP000002428; Chromosome D.
DR   Gene3D; 2.60.40.640; -; 2.
DR   InterPro; IPR014752; Arrestin-like_C.
DR   InterPro; IPR011021; Arrestin-like_N.
DR   InterPro; IPR011022; Arrestin_C-like.
DR   InterPro; IPR014756; Ig_E-set.
DR   Pfam; PF02752; Arrestin_C; 1.
DR   Pfam; PF00339; Arrestin_N; 1.
DR   SMART; SM01017; Arrestin_C; 1.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..649
FT                   /note="pH-response regulator protein palF/RIM8"
FT                   /id="PRO_0000058187"
FT   REGION          187..225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          239..262
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          446..466
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        199..225
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   649 AA;  72780 MW;  B6BFF1F8FD69D4D4 CRC64;
     MAFIKLLRKT KDEPSRLAKA VRHLQVTLDD PHATYRPRDV LFGQVLLDLK QNVANVRVRL
     TFIGEVKSKY GTAHKRGGCF MEKSTVLYGD DGDLDTDEME PTVNGLTKGV HKFPFSIRVP
     SGKKIHSSIK FERGSVSYHL MAVFESVVEP EGVSAKVRTK VNILVPIDVY RYSDVVVKTI
     LLNSNAKSKS HKINSNDHNG HLNGDVTTLT TSDGSSEGTK KTISESQIIN NLSQRQVLQK
     SKSEGSKSES IQASTGQINQ LPETSSQVSY NAVLTNGMNR DADNQTVKID VRLPHSGFVQ
     GEYIPLTINV SHYREYYHPA GVIATLVRVC KVASGRKEDT KEIYRKDICQ SISPLLIESN
     KLENTISTYL KVPNDIIASM TSLPEHFTFQ YFVEVVINLS RKLEIYSHSQ KPLSYILEKQ
     KTKKPLTIPR DLKELNLPAS VNENGAWEVP RPSLNNEKSN GGIDSSRNDF QSKFGSAFNK
     STLFGLKNID EIHVAEQTII FDDMVDVERL KRMRNVAGLS IETIIGNKRS SPAIDLAKLE
     ISKLSQGKVM KSNGTSKNTS SSGSIESNSI VRYRYISFEQ DTQSSTDSYD EDITKMGNQL
     NEWLSPANAY EEYYPVPEYS ANENVFASED KQELEYKRLH ELESDPPQF