ID   PALF_DEBHA              Reviewed;         782 AA.
AC   Q6BY20;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=pH-response regulator protein palF/RIM8;
GN   Name=RIM8; OrderedLocusNames=DEHA2A13112g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for the proteolytic cleavage of the transcription
CC       factor RIM101 in response to alkaline ambient pH. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the arrestin family. PalF/RIM8 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; CR382133; CAG84876.2; -; Genomic_DNA.
DR   RefSeq; XP_456899.2; XM_456899.1.
DR   AlphaFoldDB; Q6BY20; -.
DR   STRING; 4959.XP_456899.2; -.
DR   EnsemblFungi; CAG84876; CAG84876; DEHA2A13112g.
DR   GeneID; 2899420; -.
DR   KEGG; dha:DEHA2A13112g; -.
DR   VEuPathDB; FungiDB:DEHA2A13112g; -.
DR   eggNOG; ENOG502QTQN; Eukaryota.
DR   HOGENOM; CLU_006001_1_0_1; -.
DR   InParanoid; Q6BY20; -.
DR   OMA; YEDYYPK; -.
DR   OrthoDB; 817924at2759; -.
DR   Proteomes; UP000000599; Chromosome A.
DR   Gene3D; 2.60.40.640; -; 2.
DR   InterPro; IPR014752; Arrestin-like_C.
DR   InterPro; IPR011021; Arrestin-like_N.
DR   InterPro; IPR011022; Arrestin_C-like.
DR   Pfam; PF02752; Arrestin_C; 1.
DR   Pfam; PF00339; Arrestin_N; 1.
DR   SMART; SM01017; Arrestin_C; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..782
FT                   /note="pH-response regulator protein palF/RIM8"
FT                   /id="PRO_0000058188"
FT   REGION          173..194
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          234..300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          517..586
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          635..654
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          693..782
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        245..300
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        721..743
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        752..782
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   782 AA;  86686 MW;  5C47350516F448F9 CRC64;
     MRRAVSKIIP NGPPRFLQSG SLLSGDTNFK YRIDFNSVDE FYISLADPHR SWLPGDEISG
     QIIFISKKDL ANIVITLSLI GSVKINASSH SKLRPVKELL FHHTIKIYGD ENSGNNNENG
     EEFSNGLFKG EHRFPFIVKL PNKRVFTSID FGKGSIKYSL KAAVGNASSF ANDSPAASPL
     SDSNNNNNNT TKNNFISKTK NLNFHNSVYT SEKIITLINP IDVSKLPRSK PKRLIIKDPR
     LSKKLSRTQS STSTLNTVNT FNTLSSNNSD TTTNGEFHSN GNTPGNSASQ SNSNSPLNGL
     DNARPQVIKV ALEIPERGFL RGELIPTKLN INHSRKIQDL NGIIVTLVRV CRLSNGHENM
     VESFRKDLQQ SVLPLYVDPN TFQSEINTNL RVPADAFPTI SGCPLVSFQY FIEVLINLSG
     KSLILDSSNH HKPSISTDEA NHSLLENPSN DLKYKFNFNS NASMNQNERS GFINTDKYKR
     MKKFLLLTTE VIIGTNRSNE RSAYTSNERS NELLHDNLNS ISPTSRKSSS VSGSNDSPLL
     FNQTGSTPPS QQGHQQPMSL NPLSEAIPAN NFSTPPYFEN QQDSPLNIAD TPIPGYEEVS
     NNYHANSSLA PVQMPTHQHL SEKEQIRAHE ASLLPSAPPL DDAEETETIS PIDKNNEILE
     NIEESGEEVN QLNNESNDSA SSRHSQSFGF FTYQNSTSTT TPTNHESLEE EEEEEEDNLY
     HSNNLSNSHA EIDSESTDWV PNYETANHDI LLENDHVSTG TNMHPGRNAN SSARGPQQDN
     SS