PALI_ASHGO
ID PALI_ASHGO Reviewed; 266 AA.
AC Q759Y2;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 90.
DE RecName: Full=pH-response regulator protein palI/RIM9;
GN Name=RIM9; OrderedLocusNames=ADR141W;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Required for the proteolytic cleavage of the transcription
CC factor RIM101 in response to alkaline ambient pH. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the palI/RIM9 family. {ECO:0000305}.
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DR EMBL; AE016817; AAS52061.1; -; Genomic_DNA.
DR RefSeq; NP_984237.1; NM_209590.2.
DR AlphaFoldDB; Q759Y2; -.
DR STRING; 33169.AAS52061; -.
DR EnsemblFungi; AAS52061; AAS52061; AGOS_ADR141W.
DR GeneID; 4620398; -.
DR KEGG; ago:AGOS_ADR141W; -.
DR eggNOG; ENOG502S1J0; Eukaryota.
DR HOGENOM; CLU_084537_0_0_1; -.
DR InParanoid; Q759Y2; -.
DR OMA; DWPGWLM; -.
DR Proteomes; UP000000591; Chromosome IV.
DR GO; GO:0032153; C:cell division site; IBA:GO_Central.
DR GO; GO:0035838; C:growing cell tip; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR InterPro; IPR009571; SUR7/Rim9-like_fungi.
DR Pfam; PF06687; SUR7; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..266
FT /note="pH-response regulator protein palI/RIM9"
FT /id="PRO_0000058208"
FT TOPO_DOM 1
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 2..22
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 23..92
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 114..123
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 145..148
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 149..169
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 170..266
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 266 AA; 29530 MW; 1ACCA981D994CE48 CRC64;
MMGGMSVVEW LLLGSTTLAL LFQSFATFSV PLSNGVTLSH FNGYKFGVFG WCDTTHTHCT
PLKLGYSAED GFLFAGQDEL SLPTQAKYSL SKLLVVHPLA LCSMVVLWLM VVLSQCYKHS
DRRLTIIILW SFLTYMETLL CFLVDVLLFV PYLDWPGWLM LVSAVLVVFS SSIACLRRRT
LTSQRIEKGA KEDLELYPLY GGALGAGVVS DSESPHRPYT EGSIISVTSR ASSRLLPSAS
ELETPREELT LMDPSIKCHI ERSPMS
