ID   PALI_CANGA              Reviewed;         246 AA.
AC   Q6FU42;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=pH-response regulator protein palI/RIM9;
GN   Name=RIM9; OrderedLocusNames=CAGL0F06545g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for the proteolytic cleavage of the transcription
CC       factor RIM101 in response to alkaline ambient pH. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the palI/RIM9 family. {ECO:0000305}.
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DR   EMBL; CR380952; CAG59176.1; -; Genomic_DNA.
DR   RefSeq; XP_446252.1; XM_446252.1.
DR   AlphaFoldDB; Q6FU42; -.
DR   STRING; 5478.XP_446252.1; -.
DR   EnsemblFungi; CAG59176; CAG59176; CAGL0F06545g.
DR   GeneID; 2887915; -.
DR   KEGG; cgr:CAGL0F06545g; -.
DR   CGD; CAL0130890; CAGL0F06545g.
DR   VEuPathDB; FungiDB:CAGL0F06545g; -.
DR   eggNOG; ENOG502S1J0; Eukaryota.
DR   HOGENOM; CLU_084537_1_0_1; -.
DR   InParanoid; Q6FU42; -.
DR   OMA; DWPGWLM; -.
DR   Proteomes; UP000002428; Chromosome F.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030437; P:ascospore formation; IEA:EnsemblFungi.
DR   InterPro; IPR009571; SUR7/Rim9-like_fungi.
DR   Pfam; PF06687; SUR7; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..246
FT                   /note="pH-response regulator protein palI/RIM9"
FT                   /id="PRO_0000058210"
FT   TOPO_DOM        1..8
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        30..91
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        92..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        113..129
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        130..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        151..154
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        155..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        176..246
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   246 AA;  28186 MW;  ABB35C61B072541E CRC64;
     MHLFDLRTLL AILVSICVVF QAFPLATVPL NKNLILGQYM GYHFGVFGWC FVDKGVTIAC
     HCKFRPDSIE TYKYTDQLLF PSLYKVTIST LLVVHPVSFA FTCILWIMAL IIRLSRFGRC
     PIFILSAATW SLAAFLLALL SALVDLLLFV NKLKWPGWLV LASVPLMAIC CSWLWSLRRQ
     VSAIFYERKA YATQTYSRFD SMELSHIDTK FSDDQSIYET YTLERVPYSK NEAIEEPALT
     YYTSSS