PAL_BRUME
ID PAL_BRUME Reviewed; 168 AA.
AC P0A3S7; Q44662;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Peptidoglycan-associated lipoprotein {ECO:0000255|HAMAP-Rule:MF_02204};
DE Short=PAL {ECO:0000255|HAMAP-Rule:MF_02204};
DE AltName: Full=16.5 kDa minor OMP;
DE Short=16 kDa OMP;
DE AltName: Full=Minor outer membrane protein Omp16;
DE AltName: Full=Outer membrane lipoprotein Omp16;
DE Flags: Precursor;
GN Name=pal {ECO:0000255|HAMAP-Rule:MF_02204}; Synonyms=omp16;
GN OrderedLocusNames=BMEI0340;
OS Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=224914;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=16M / ATCC 23456 / NCTC 10094;
RX PubMed=11756688; DOI=10.1073/pnas.221575398;
RA DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J.,
RA Haselkorn R., Kyrpides N.C., Overbeek R.;
RT "The genome sequence of the facultative intracellular pathogen Brucella
RT melitensis.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=16M / ATCC 23456 / NCTC 10094;
RA Tibor A., Aidant N., Letesson J.-J.;
RT "The tol-pal region in Brucella encodes homologs of the Tol-Pal system of
RT E. coli.";
RL Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP CHARACTERIZATION.
RX PubMed=10456959; DOI=10.1128/iai.67.9.4960-4962.1999;
RA Tibor A., Decelle B., Letesson J.-J.;
RT "Outer membrane proteins Omp10, Omp16, and Omp19 of Brucella spp. are
RT lipoproteins.";
RL Infect. Immun. 67:4960-4962(1999).
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC Rule:MF_02204}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000255|HAMAP-Rule:MF_02204}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC Rule:MF_02204}; Lipid-anchor {ECO:0000255|HAMAP-Rule:MF_02204}.
CC -!- PTM: The N-terminus is blocked.
CC -!- SIMILARITY: Belongs to the Pal lipoprotein family. {ECO:0000255|HAMAP-
CC Rule:MF_02204}.
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DR EMBL; AF358662; AAK48919.1; -; Genomic_DNA.
DR EMBL; AE008917; AAL51521.1; -; Genomic_DNA.
DR PIR; AF3294; AF3294.
DR RefSeq; WP_002966947.1; NZ_GG703781.1.
DR AlphaFoldDB; P0A3S7; -.
DR SMR; P0A3S7; -.
DR STRING; 224914.BMEI0340; -.
DR PRIDE; P0A3S7; -.
DR EnsemblBacteria; AAL51521; AAL51521; BMEI0340.
DR GeneID; 45124999; -.
DR GeneID; 55591316; -.
DR KEGG; bme:BMEI0340; -.
DR PATRIC; fig|224914.52.peg.1152; -.
DR eggNOG; COG2885; Bacteria.
DR OMA; TPENAGM; -.
DR PhylomeDB; P0A3S7; -.
DR Proteomes; UP000000419; Chromosome I.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR CDD; cd07185; OmpA_C-like; 1.
DR Gene3D; 3.30.1330.60; -; 1.
DR HAMAP; MF_02204; Pal; 1.
DR InterPro; IPR006664; OMP_bac.
DR InterPro; IPR006665; OmpA-like.
DR InterPro; IPR006690; OMPA-like_CS.
DR InterPro; IPR036737; OmpA-like_sf.
DR InterPro; IPR039001; Pal.
DR InterPro; IPR014169; Pal_lipo_C.
DR Pfam; PF00691; OmpA; 1.
DR PRINTS; PR01021; OMPADOMAIN.
DR SUPFAM; SSF103088; SSF103088; 1.
DR TIGRFAMs; TIGR02802; Pal_lipo; 1.
DR PROSITE; PS01068; OMPA_1; 1.
DR PROSITE; PS51123; OMPA_2; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 1: Evidence at protein level;
KW Cell cycle; Cell division; Cell outer membrane; Lipoprotein; Membrane;
KW Palmitate; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02204, ECO:0000305"
FT CHAIN 25..168
FT /note="Peptidoglycan-associated lipoprotein"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02204"
FT /id="PRO_0000020129"
FT DOMAIN 51..167
FT /note="OmpA-like"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02204"
FT LIPID 25
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02204"
FT LIPID 25
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02204"
SQ SEQUENCE 168 AA; 18233 MW; 17F75F4F05EB1DD8 CRC64;
MRRIQSIARS PIAIALFMSL AVAGCASKKN LPNNAGDLGL GAGAATPGSS QDFTVNVGDR
IFFDLDSSLI RADAQQTLSK QAQWLQRYPQ YSITIEGHAD ERGTREYNLA LGQRRAAATR
DFLASRGVPT NRMRTISYGN ERPVAVCDAD TCWSQNRRAV TVLNGAGR
