ID   PAL_LEGPN               Reviewed;         176 AA.
AC   P26493;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=Peptidoglycan-associated lipoprotein {ECO:0000255|HAMAP-Rule:MF_02204};
DE            Short=PAL {ECO:0000255|HAMAP-Rule:MF_02204};
DE   AltName: Full=19 kDa surface antigen;
DE   AltName: Full=PPL;
DE   Flags: Precursor;
GN   Name=pal {ECO:0000255|HAMAP-Rule:MF_02204}; Synonyms=pplA;
OS   Legionella pneumophila.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=446;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=AA100 / Serogroup 1;
RX   PubMed=1766377; DOI=10.1111/j.1365-2958.1991.tb00824.x;
RA   Engleberg N.C., Howe D.C., Rogers J.E., Arroyo J., Eisenstein B.I.;
RT   "Characterization of a Legionella pneumophila gene encoding a lipoprotein
RT   antigen.";
RL   Mol. Microbiol. 5:2021-2029(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1855972; DOI=10.1128/iai.59.8.2515-2521.1991;
RA   Ludwig B., Schmid A., Marre R., Hacker J.;
RT   "Cloning, genetic analysis, and nucleotide sequence of a determinant coding
RT   for a 19-kilodalton peptidoglycan-associated protein (Ppl) of Legionella
RT   pneumophila.";
RL   Infect. Immun. 59:2515-2521(1991).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity (By similarity). Very strongly
CC       associated with the peptidoglycan. {ECO:0000255|HAMAP-Rule:MF_02204}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_02204}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_02204}; Lipid-anchor {ECO:0000255|HAMAP-Rule:MF_02204}.
CC   -!- SIMILARITY: Belongs to the Pal lipoprotein family. {ECO:0000255|HAMAP-
CC       Rule:MF_02204}.
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DR   EMBL; X60543; CAA43033.1; -; Genomic_DNA.
DR   PIR; A60337; A60337.
DR   RefSeq; WP_010947759.1; NZ_UGOV01000002.1.
DR   AlphaFoldDB; P26493; -.
DR   SMR; P26493; -.
DR   STRING; 91892.BIZ52_10025; -.
DR   GeneID; 66491175; -.
DR   eggNOG; COG2885; Bacteria.
DR   OMA; ESNESCW; -.
DR   OrthoDB; 1544679at2; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   CDD; cd07185; OmpA_C-like; 1.
DR   Gene3D; 3.30.1330.60; -; 1.
DR   HAMAP; MF_02204; Pal; 1.
DR   InterPro; IPR006664; OMP_bac.
DR   InterPro; IPR006665; OmpA-like.
DR   InterPro; IPR006690; OMPA-like_CS.
DR   InterPro; IPR036737; OmpA-like_sf.
DR   InterPro; IPR039001; Pal.
DR   InterPro; IPR014169; Pal_lipo_C.
DR   Pfam; PF00691; OmpA; 1.
DR   PRINTS; PR01021; OMPADOMAIN.
DR   SUPFAM; SSF103088; SSF103088; 1.
DR   TIGRFAMs; TIGR02802; Pal_lipo; 1.
DR   PROSITE; PS01068; OMPA_1; 1.
DR   PROSITE; PS51123; OMPA_2; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell outer membrane; Lipoprotein; Membrane;
KW   Palmitate; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02204"
FT   CHAIN           22..176
FT                   /note="Peptidoglycan-associated lipoprotein"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02204"
FT                   /id="PRO_0000020124"
FT   DOMAIN          60..176
FT                   /note="OmpA-like"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02204"
FT   LIPID           22
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02204"
FT   LIPID           22
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02204"
SQ   SEQUENCE   176 AA;  18911 MW;  7D9C3EBECBE621DB CRC64;
     MKAGSFYKLG LLVASAVLVA ACSKTPGSAD GGAAVGDGDA TAQGLGQMTH FAGQEPGESY
     TTQAPHNQLY LFAYDDSTLA SKYLPSVNAQ AEYLKTHPGA RVMIAGHTDE RGSREYNVAL
     GERRADTVAE ILRMAGVSRQ QIRVVSYGKE RPANYGHDEA SHAQNRRVEF IYEATR