ID   PAM17_ASPFU             Reviewed;         247 AA.
AC   Q4WKN3;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Presequence translocated-associated motor subunit pam17, mitochondrial;
DE   Flags: Precursor;
GN   Name=pam17; ORFNames=AFUA_1G01870;
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=330879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA   Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA   Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA   Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA   Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA   Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA   Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA   O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA   Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA   Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA   Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA   Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA   Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA   Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA   Barrell B.G., Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- FUNCTION: Component of the PAM complex, a complex required for the
CC       translocation of transit peptide-containing proteins from the inner
CC       membrane into the mitochondrial matrix in an ATP-dependent manner.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the PAM complex, at least composed of mtHsp70,
CC       MGE1/mgeA, tim44, PAM16/pamP, PAM17/pamQ and PAM18/pamR. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PAM17 family. {ECO:0000305}.
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DR   EMBL; AAHF01000007; EAL87899.1; -; Genomic_DNA.
DR   RefSeq; XP_749937.1; XM_744844.1.
DR   AlphaFoldDB; Q4WKN3; -.
DR   STRING; 746128.CADAFUBP00000221; -.
DR   EnsemblFungi; EAL87899; EAL87899; AFUA_1G01870.
DR   GeneID; 3507834; -.
DR   KEGG; afm:AFUA_1G01870; -.
DR   VEuPathDB; FungiDB:Afu1g01870; -.
DR   eggNOG; ENOG502S1B1; Eukaryota.
DR   HOGENOM; CLU_068297_0_1_1; -.
DR   InParanoid; Q4WKN3; -.
DR   OMA; YKPSVNT; -.
DR   OrthoDB; 1353188at2759; -.
DR   Proteomes; UP000002530; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0001405; C:PAM complex, Tim23 associated import motor; IBA:GO_Central.
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; IBA:GO_Central.
DR   InterPro; IPR013875; Pam17.
DR   PANTHER; PTHR28021; PTHR28021; 1.
DR   Pfam; PF08566; Pam17; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Protein transport;
KW   Reference proteome; Transit peptide; Translocation; Transmembrane;
KW   Transmembrane helix; Transport.
FT   TRANSIT         1..49
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           50..247
FT                   /note="Presequence translocated-associated motor subunit
FT                   pam17, mitochondrial"
FT                   /id="PRO_0000043150"
FT   TRANSMEM        112..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   247 AA;  27663 MW;  1C13E9E6ABD4E044 CRC64;
     MHLTLMNGTL RTAALSGRFA LASPSPLPTA TPLFQCCQKM SLRTQARPVS TSTTRILLKP
     SLRPQTSSMC LSPIFRKTAF RLNSTAANAS RAEVPKLDWN SFFKLRASRR RYTLASSIIA
     SMASTIIGVQ ILSEQDLESL GAQVMGLDPF VVLGLATATC GAVGWLAGPF LGNAIWRLVY
     RKYKPAFLMR EKEFFDRIKR FRVDPSSNSI ANPVPDYYGE KIGSVQGYRQ WLKDQRAYNR
     KRRSFII