ID   PAM17_CANAL             Reviewed;         185 AA.
AC   Q5AEM8; A0A1D8PJG3;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2017, sequence version 3.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Presequence translocated-associated motor subunit PAM17, mitochondrial;
DE   Flags: Precursor;
GN   Name=PAM17; OrderedLocusNames=CAALFM_C302500WA;
GN   ORFNames=CaO19.240, CaO19.7870;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Component of the PAM complex, a complex required for the
CC       translocation of transit peptide-containing proteins from the inner
CC       membrane into the mitochondrial matrix in an ATP-dependent manner.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the PAM complex, at least composed of mtHsp70
CC       (SSC1), MGE1, TIM44, PAM16, PAM17 and PAM18. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PAM17 family. {ECO:0000305}.
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DR   EMBL; CP017625; AOW28285.1; -; Genomic_DNA.
DR   RefSeq; XP_719939.2; XM_714846.2.
DR   AlphaFoldDB; Q5AEM8; -.
DR   STRING; 237561.Q5AEM8; -.
DR   PRIDE; Q5AEM8; -.
DR   GeneID; 3638369; -.
DR   KEGG; cal:CAALFM_C302500WA; -.
DR   CGD; CAL0000186714; PAM17.
DR   VEuPathDB; FungiDB:C3_02500W_A; -.
DR   eggNOG; ENOG502S1B1; Eukaryota.
DR   HOGENOM; CLU_068297_2_0_1; -.
DR   InParanoid; Q5AEM8; -.
DR   OrthoDB; 1353188at2759; -.
DR   PRO; PR:Q5AEM8; -.
DR   Proteomes; UP000000559; Chromosome 3.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0001405; C:PAM complex, Tim23 associated import motor; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IDA:CGD.
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; IBA:GO_Central.
DR   InterPro; IPR013875; Pam17.
DR   PANTHER; PTHR28021; PTHR28021; 1.
DR   Pfam; PF08566; Pam17; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Protein transport;
KW   Reference proteome; Transit peptide; Translocation; Transmembrane;
KW   Transmembrane helix; Transport.
FT   TRANSIT         1..52
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           53..185
FT                   /note="Presequence translocated-associated motor subunit
FT                   PAM17, mitochondrial"
FT                   /id="PRO_0000043151"
FT   TRANSMEM        55..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   185 AA;  21051 MW;  B96602619B02BBBB CRC64;
     MFSLGVQSRL FTRRALFSGF RFNSTTTTTT TASQPRLTWV DYFQLKKQNN RINTIAGVFT
     GLGGAFITLS YLGNIEIDVE KPIMGFDPLM VMGGAVILGG LVGFLVGPFI GSSIFRLTNR
     AQLKQFELKN TEFLSRLRIK RPDPSSQSFS NPIPDYYGEK IYSLKDYKQW LRDCNAFRRK
     SKEFL