PAM17_EMENI
ID PAM17_EMENI Reviewed; 252 AA.
AC C8VTR5; Q5BGF9;
DT 19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT 03-NOV-2009, sequence version 1.
DT 25-MAY-2022, entry version 50.
DE RecName: Full=Presequence translocated-associated motor subunit pam17, mitochondrial;
DE Flags: Precursor;
GN Name=pam17; ORFNames=AN10067;
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- FUNCTION: Component of the PAM complex, a complex required for the
CC translocation of transit peptide-containing proteins from the inner
CC membrane into the mitochondrial matrix in an ATP-dependent manner.
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of the PAM complex, at least composed of mtHsp70,
CC MGE1/mgeA, tim44, PAM16/pamP, PAM17/pamQ and PAM18/pamR. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PAM17 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAA65777.1; Type=Erroneous gene model prediction; Note=The predicted gene AN0371 has been split into 2 genes: AN10067 and AN10074.; Evidence={ECO:0000305};
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DR EMBL; AACD01000006; EAA65777.1; ALT_SEQ; Genomic_DNA.
DR EMBL; BN001308; CBF89621.1; -; Genomic_DNA.
DR AlphaFoldDB; C8VTR5; -.
DR STRING; 162425.CADANIAP00002331; -.
DR EnsemblFungi; CBF89621; CBF89621; ANIA_10067.
DR EnsemblFungi; EAA65777; EAA65777; AN0371.2.
DR VEuPathDB; FungiDB:AN10067; -.
DR eggNOG; ENOG502S1B1; Eukaryota.
DR HOGENOM; CLU_413324_0_0_1; -.
DR InParanoid; C8VTR5; -.
DR OMA; YKPSVNT; -.
DR OrthoDB; 1353188at2759; -.
DR Proteomes; UP000000560; Chromosome VIII.
DR Proteomes; UP000005890; Unassembled WGS sequence.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0001405; C:PAM complex, Tim23 associated import motor; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR013875; Pam17.
DR PANTHER; PTHR28021; PTHR28021; 1.
DR Pfam; PF08566; Pam17; 1.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Protein transport;
KW Reference proteome; Transit peptide; Translocation; Transmembrane;
KW Transmembrane helix; Transport.
FT TRANSIT 1..87
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 88..252
FT /note="Presequence translocated-associated motor subunit
FT pam17, mitochondrial"
FT /id="PRO_0000043155"
FT TRANSMEM 117..137
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 155..175
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 252 AA; 27812 MW; 544ABC39F40F2675 CRC64;
MHTTLLSNSM RGAALCTRVS STTLNPVTLQ TSAIYQTISL KNQTRPSSTS TVRFLKASPT
LRTSSARPQA QIATSCINAK NTISVRSNST TSTSAREEAA KLDWNSYFKL RASRRRYTLA
SSIVSSAVST VVGVQVLSSQ NLENLGAQVM GLDPFVVLGM ATAACGAVGW LVGPFLGNAV
WGLVNRSYKK AFLVKEKEFF DRIKRYRVDP SSNSMTNPVP DYYGEKIGSV QGYRQWLKDQ
RAYNRKRRSF IK
