ID   PAM17_KLULA             Reviewed;         196 AA.
AC   Q6CXR8;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Presequence translocated-associated motor subunit PAM17, mitochondrial;
DE   Flags: Precursor;
GN   Name=PAM17; OrderedLocusNames=KLLA0A06083g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the PAM complex, a complex required for the
CC       translocation of transit peptide-containing proteins from the inner
CC       membrane into the mitochondrial matrix in an ATP-dependent manner.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the PAM complex, at least composed of mtHsp70
CC       (SSC1), MGE1, TIM44, PAM16, PAM17 and PAM18. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PAM17 family. {ECO:0000305}.
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DR   EMBL; CR382121; CAH02859.1; -; Genomic_DNA.
DR   RefSeq; XP_451271.1; XM_451271.1.
DR   AlphaFoldDB; Q6CXR8; -.
DR   STRING; 28985.XP_451271.1; -.
DR   EnsemblFungi; CAH02859; CAH02859; KLLA0_A06083g.
DR   GeneID; 2896450; -.
DR   KEGG; kla:KLLA0_A06083g; -.
DR   eggNOG; ENOG502S1B1; Eukaryota.
DR   HOGENOM; CLU_068297_2_0_1; -.
DR   InParanoid; Q6CXR8; -.
DR   OMA; YKPSVNT; -.
DR   Proteomes; UP000000598; Chromosome A.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0001405; C:PAM complex, Tim23 associated import motor; IEA:EnsemblFungi.
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; IEA:EnsemblFungi.
DR   InterPro; IPR013875; Pam17.
DR   PANTHER; PTHR28021; PTHR28021; 1.
DR   Pfam; PF08566; Pam17; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Protein transport;
KW   Reference proteome; Transit peptide; Translocation; Transmembrane;
KW   Transmembrane helix; Transport.
FT   TRANSIT         1..33
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           34..196
FT                   /note="Presequence translocated-associated motor subunit
FT                   PAM17, mitochondrial"
FT                   /id="PRO_0000043157"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   196 AA;  22071 MW;  CD035E6BF5A7DFB0 CRC64;
     MLRLGINLQN RLLVGLNGQS LLKRAVTRNA VAIRMNSTNA GKTASHEMTW PEFFKLRKKE
     RVFNTASSVA TAIVFVNGSW FYFSTLEIDP TQTIFGFDPL MAITAGMITC AAVGWLLGPI
     VGTALFKATS GPKLLQFQEK QLSFLAKIQK NRVNPQSQSF SNPVPDYYGE KINSIPQYRQ
     WLRDCHSYKR KASEFL