ID   PAM17_NEUCR             Reviewed;         267 AA.
AC   Q7SEE1;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Presequence translocated-associated motor subunit pam17, mitochondrial;
DE   Flags: Precursor;
GN   Name=pam17; ORFNames=NCU00737;
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA   Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA   Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA   Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA   Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA   Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA   Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
CC   -!- FUNCTION: Component of the PAM complex, a complex required for the
CC       translocation of transit peptide-containing proteins from the inner
CC       membrane into the mitochondrial matrix in an ATP-dependent manner.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the PAM complex, at least composed of hsp70-
CC       5/ssc1, grpe/mge1, tim44, un-4/pam16, pam17 and tim14/pam18.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PAM17 family. {ECO:0000305}.
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DR   EMBL; CM002236; EAA35154.1; -; Genomic_DNA.
DR   RefSeq; XP_964390.1; XM_959297.3.
DR   AlphaFoldDB; Q7SEE1; -.
DR   STRING; 5141.EFNCRP00000000629; -.
DR   EnsemblFungi; EAA35154; EAA35154; NCU00737.
DR   GeneID; 3880540; -.
DR   KEGG; ncr:NCU00737; -.
DR   VEuPathDB; FungiDB:NCU00737; -.
DR   HOGENOM; CLU_068297_0_1_1; -.
DR   InParanoid; Q7SEE1; -.
DR   Proteomes; UP000001805; Chromosome 1, Linkage Group I.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0001405; C:PAM complex, Tim23 associated import motor; IBA:GO_Central.
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; IBA:GO_Central.
DR   InterPro; IPR013875; Pam17.
DR   PANTHER; PTHR28021; PTHR28021; 1.
DR   Pfam; PF08566; Pam17; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Protein transport;
KW   Reference proteome; Transit peptide; Translocation; Transmembrane;
KW   Transmembrane helix; Transport.
FT   TRANSIT         1..86
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           87..267
FT                   /note="Presequence translocated-associated motor subunit
FT                   pam17, mitochondrial"
FT                   /id="PRO_0000043158"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        171..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          71..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        71..94
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   267 AA;  28607 MW;  945D92CAC79C7013 CRC64;
     MLSSTATTML RAGVSRSSGA LQPMLLRSAA CPCSPFSMNT KLSQPTSVRP LSTSPSALVL
     RFRAQQQAQL AQQQLRRASS SSSSSSSSTR PRSDAELDAN AAEAAAAAQS AAHAGEPVLD
     WNTFFKLRKT RRRVQLAFSV IMTLITSGAG GAVLSTGVAD AMVAQVPLEP MFAVGLMTAS
     FGALGWLMGP AMGGMVFNAL KSKYRGQMEI KEGQFFARIK KHRVDPSASS MGNPVPDFYG
     EKISSVAGYR QWLKDQRAFN KKRTTFV