PAM17_USTMA
ID PAM17_USTMA Reviewed; 232 AA.
AC Q4P983; A0A0D1DX15;
DT 06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 1.
DT 25-MAY-2022, entry version 79.
DE RecName: Full=Presequence translocated-associated motor subunit PAM17, mitochondrial;
DE Flags: Precursor;
GN Name=PAM17; ORFNames=UMAG_03330;
OS Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX NCBI_TaxID=237631;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=521 / FGSC 9021;
RX PubMed=17080091; DOI=10.1038/nature05248;
RA Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA Birren B.W.;
RT "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT maydis.";
RL Nature 444:97-101(2006).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=521 / FGSC 9021;
RA Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the PAM complex, a complex required for the
CC translocation of transit peptide-containing proteins from the inner
CC membrane into the mitochondrial matrix in an ATP-dependent manner.
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of the PAM complex, at least composed of mtHsp70
CC (SSC1), MGE1, TIM44, PAM16, PAM17 and PAM18. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PAM17 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM003147; KIS68764.1; -; Genomic_DNA.
DR RefSeq; XP_011389726.1; XM_011391424.1.
DR AlphaFoldDB; Q4P983; -.
DR STRING; 5270.UM03330P0; -.
DR EnsemblFungi; KIS68764; KIS68764; UMAG_03330.
DR GeneID; 23563814; -.
DR KEGG; uma:UMAG_03330; -.
DR VEuPathDB; FungiDB:UMAG_03330; -.
DR eggNOG; ENOG502S1B1; Eukaryota.
DR HOGENOM; CLU_068297_1_0_1; -.
DR InParanoid; Q4P983; -.
DR OMA; YKPSVNT; -.
DR OrthoDB; 1353188at2759; -.
DR Proteomes; UP000000561; Chromosome 8.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0001405; C:PAM complex, Tim23 associated import motor; IBA:GO_Central.
DR GO; GO:0030150; P:protein import into mitochondrial matrix; IBA:GO_Central.
DR InterPro; IPR013875; Pam17.
DR PANTHER; PTHR28021; PTHR28021; 1.
DR Pfam; PF08566; Pam17; 1.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Protein transport;
KW Reference proteome; Transit peptide; Translocation; Transmembrane;
KW Transmembrane helix; Transport.
FT TRANSIT 1..40
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 41..232
FT /note="Presequence translocated-associated motor subunit
FT PAM17, mitochondrial"
FT /id="PRO_0000043160"
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 140..160
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 232 AA; 24904 MW; 18BE0D19A367D340 CRC64;
MPVAIAAARY AALSAGASSS RSAIMLSSSH RALSTSSKVA SSSSSSNRGT FSPTSPILFS
ASSSSSSSSS PSSSRELSHL SWDKYLQLRR SRRLAGMVTT IPTTLLAGAA AGSYFLTLEL
DPTNAIAGLD PVYINAGLTL ACTGLGWLIG PTVGNSIWGL LHRSDAKQIA QKDHDFYEHI
KRNRVDPTRQ SVQNPVPDYY GEKIGSIKQY RQWLRDQAAF RRKAAHGLEQ DA