A32_VAR67
ID A32_VAR67 Reviewed; 270 AA.
AC P0DTA0; P33849;
DT 16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT 16-OCT-2019, sequence version 1.
DT 03-AUG-2022, entry version 9.
DE RecName: Full=Protein A32;
GN ORFNames=A32L, A35L;
OS Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX NCBI_TaxID=587200;
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1666548;
RA Shchelkunov S.N., Marennikova S.S., Totmenin A.V., Blinov V.M.,
RA Chizhikov V.E., Gutorov V.V., Safronov P.F., Pozdnyakov S.G.,
RA Shelukhina E.M., Gashnikov P.V., Anjaparidze O.G., Sandakhchiev L.S.;
RT "Creation of a clone library of fragments from the natural variola virus
RT and study of the structural and functional organization of viral genes from
RT a circle of hosts.";
RL Dokl. Akad. Nauk SSSR 321:402-406(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8384129; DOI=10.1016/0014-5793(93)80041-r;
RA Shchelkunov S.N., Blinov V.M., Sandakhchiev L.S.;
RT "Genes of variola and vaccinia viruses necessary to overcome the host
RT protective mechanisms.";
RL FEBS Lett. 319:80-83(1993).
CC -!- FUNCTION: Participates in viral DNA packaging and virion morphogenesis.
CC {ECO:0000250}.
CC -!- SUBUNIT: Interacts with A11. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the chordopoxvirinae A32 protein family.
CC {ECO:0000305}.
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DR EMBL; X69198; CAA49080.1; -; Genomic_DNA.
DR EMBL; X67115; CAA47506.1; -; Genomic_DNA.
DR PIR; I36851; I36851.
DR RefSeq; NP_042183.1; NC_001611.1.
DR GeneID; 1486513; -.
DR KEGG; vg:1486513; -.
DR Proteomes; UP000002060; Genome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR006758; A32L.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF04665; Pox_A32; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 3: Inferred from homology;
KW ATP-binding; Nucleotide-binding; Reference proteome.
FT CHAIN 1..270
FT /note="Protein A32"
FT /id="PRO_0000099315"
FT BINDING 25..32
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 270 AA; 30991 MW; D20BF4173F4EB4CA CRC64;
MNCFQEKQFL RENLLKMPFR MVLTGGSGSG KTIYLLSLFS TLVKKYKHIF LFTPVYNPDY
DGYIWPNHIN FVSSQESLEY NLIRTKSNIE KCITVAQNHK KSAHFLLIFD DVGDKLSKCN
TLIEFLNFGR HLNTSIILLC QTYRHVPILG RANITHFCSF NISISDAENM LRSMPVKGKR
KDILNMLNMI QTVRSNNRLA IIIEDSVFCE GELRICTDTA DKDVIEQKLN IDILVNQYSH
MKKNLNTILE STKTKLCNSD QSSSSKNVSS