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A32_VAR67
ID   A32_VAR67               Reviewed;         270 AA.
AC   P0DTA0; P33849;
DT   16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT   16-OCT-2019, sequence version 1.
DT   03-AUG-2022, entry version 9.
DE   RecName: Full=Protein A32;
GN   ORFNames=A32L, A35L;
OS   Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=587200;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1666548;
RA   Shchelkunov S.N., Marennikova S.S., Totmenin A.V., Blinov V.M.,
RA   Chizhikov V.E., Gutorov V.V., Safronov P.F., Pozdnyakov S.G.,
RA   Shelukhina E.M., Gashnikov P.V., Anjaparidze O.G., Sandakhchiev L.S.;
RT   "Creation of a clone library of fragments from the natural variola virus
RT   and study of the structural and functional organization of viral genes from
RT   a circle of hosts.";
RL   Dokl. Akad. Nauk SSSR 321:402-406(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8384129; DOI=10.1016/0014-5793(93)80041-r;
RA   Shchelkunov S.N., Blinov V.M., Sandakhchiev L.S.;
RT   "Genes of variola and vaccinia viruses necessary to overcome the host
RT   protective mechanisms.";
RL   FEBS Lett. 319:80-83(1993).
CC   -!- FUNCTION: Participates in viral DNA packaging and virion morphogenesis.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with A11. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae A32 protein family.
CC       {ECO:0000305}.
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DR   EMBL; X69198; CAA49080.1; -; Genomic_DNA.
DR   EMBL; X67115; CAA47506.1; -; Genomic_DNA.
DR   PIR; I36851; I36851.
DR   RefSeq; NP_042183.1; NC_001611.1.
DR   GeneID; 1486513; -.
DR   KEGG; vg:1486513; -.
DR   Proteomes; UP000002060; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR006758; A32L.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF04665; Pox_A32; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..270
FT                   /note="Protein A32"
FT                   /id="PRO_0000099315"
FT   BINDING         25..32
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   270 AA;  30991 MW;  D20BF4173F4EB4CA CRC64;
     MNCFQEKQFL RENLLKMPFR MVLTGGSGSG KTIYLLSLFS TLVKKYKHIF LFTPVYNPDY
     DGYIWPNHIN FVSSQESLEY NLIRTKSNIE KCITVAQNHK KSAHFLLIFD DVGDKLSKCN
     TLIEFLNFGR HLNTSIILLC QTYRHVPILG RANITHFCSF NISISDAENM LRSMPVKGKR
     KDILNMLNMI QTVRSNNRLA IIIEDSVFCE GELRICTDTA DKDVIEQKLN IDILVNQYSH
     MKKNLNTILE STKTKLCNSD QSSSSKNVSS
 
 
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