A32_VARV
ID A32_VARV Reviewed; 270 AA.
AC P0DSZ9; P33849;
DT 16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT 16-OCT-2019, sequence version 1.
DT 03-AUG-2022, entry version 12.
DE RecName: Full=Protein A32;
GN ORFNames=A32L, A35L;
OS Variola virus.
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX NCBI_TaxID=10255;
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Harvey;
RX PubMed=1331292; DOI=10.1099/0022-1317-73-11-2887;
RA Aguado B., Selmes I.P., Smith G.L.;
RT "Nucleotide sequence of 21.8 kbp of variola major virus strain Harvey and
RT comparison with vaccinia virus.";
RL J. Gen. Virol. 73:2887-2902(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Bangladesh-1975;
RX PubMed=8264798; DOI=10.1038/366748a0;
RA Massung R.F., Esposito J.J., Liu L.I., Qi J., Utterback T.R., Knight J.C.,
RA Aubin L., Yuran T.E., Parsons J.M., Loparev V.N., Selivanov N.A.,
RA Cavallaro K.F., Kerlavage A.R., Mahy B.W.J., Venter J.C.;
RT "Potential virulence determinants in terminal regions of variola smallpox
RT virus genome.";
RL Nature 366:748-751(1993).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Garcia-1966;
RA Shchelkunov S.N., Totmenin A.V., Resenchuk S.M., Blinov V.M.,
RA Sandakhchiev L.S.;
RL Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Participates in viral DNA packaging and virion morphogenesis.
CC {ECO:0000250}.
CC -!- SUBUNIT: Interacts with A11. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the chordopoxvirinae A32 protein family.
CC {ECO:0000305}.
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DR EMBL; L22579; AAA60887.1; -; Genomic_DNA.
DR EMBL; X76266; CAA53861.1; -; Genomic_DNA.
DR PIR; A72168; A72168.
DR PIR; T28577; T28577.
DR RefSeq; NP_042183.1; NC_001611.1.
DR GeneID; 1486513; -.
DR KEGG; vg:1486513; -.
DR Proteomes; UP000119805; Genome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR006758; A32L.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF04665; Pox_A32; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 3: Inferred from homology;
KW ATP-binding; Nucleotide-binding.
FT CHAIN 1..270
FT /note="Protein A32"
FT /id="PRO_0000448229"
FT BINDING 25..32
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 270 AA; 30991 MW; D20BF4173F4EB4CA CRC64;
MNCFQEKQFL RENLLKMPFR MVLTGGSGSG KTIYLLSLFS TLVKKYKHIF LFTPVYNPDY
DGYIWPNHIN FVSSQESLEY NLIRTKSNIE KCITVAQNHK KSAHFLLIFD DVGDKLSKCN
TLIEFLNFGR HLNTSIILLC QTYRHVPILG RANITHFCSF NISISDAENM LRSMPVKGKR
KDILNMLNMI QTVRSNNRLA IIIEDSVFCE GELRICTDTA DKDVIEQKLN IDILVNQYSH
MKKNLNTILE STKTKLCNSD QSSSSKNVSS