ID   ASNC_HAEIN              Reviewed;         150 AA.
AC   P44337;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Regulatory protein AsnC;
GN   Name=asnC; OrderedLocusNames=HI_0563;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Activator of asnA transcription. {ECO:0000250}.
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DR   EMBL; L42023; AAC22221.1; -; Genomic_DNA.
DR   PIR; G64077; G64077.
DR   RefSeq; NP_438720.1; NC_000907.1.
DR   RefSeq; WP_005649540.1; NC_000907.1.
DR   AlphaFoldDB; P44337; -.
DR   SMR; P44337; -.
DR   STRING; 71421.HI_0563; -.
DR   EnsemblBacteria; AAC22221; AAC22221; HI_0563.
DR   KEGG; hin:HI_0563; -.
DR   PATRIC; fig|71421.8.peg.583; -.
DR   eggNOG; COG1522; Bacteria.
DR   HOGENOM; CLU_091233_5_0_6; -.
DR   OMA; EDCWFIA; -.
DR   PhylomeDB; P44337; -.
DR   BioCyc; HINF71421:G1GJ1-575-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProt.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR000485; AsnC-type_HTH_dom.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR019888; Tscrpt_reg_AsnC-like.
DR   InterPro; IPR019887; Tscrpt_reg_AsnC/Lrp_C.
DR   InterPro; IPR019885; Tscrpt_reg_HTH_AsnC-type_CS.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01037; AsnC_trans_reg; 1.
DR   Pfam; PF13404; HTH_AsnC-type; 1.
DR   PRINTS; PR00033; HTHASNC.
DR   SMART; SM00344; HTH_ASNC; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF54909; SSF54909; 1.
DR   PROSITE; PS00519; HTH_ASNC_1; 1.
DR   PROSITE; PS50956; HTH_ASNC_2; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..150
FT                   /note="Regulatory protein AsnC"
FT                   /id="PRO_0000111723"
FT   DOMAIN          4..65
FT                   /note="HTH asnC-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00319"
FT   DNA_BIND        23..42
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00319"
SQ   SEQUENCE   150 AA;  17060 MW;  1DC36CB301A25146 CRC64;
     MHNIDSLDQK ILRVLTKDAR TPYAEMAKNF GVSPGTIHVR VEKMRQSGII KGTKVIIDER
     KLGYDVCCFI GIILKSAKDY EKVIKKLESF DEVVEAYYTT GNYSIFLKVM THTIAELHSV
     LATKIQLIDE IQSTETLISM QNPILRDIKP