PAP2_ARATH
ID PAP2_ARATH Reviewed; 310 AA.
AC O49629; Q8LFZ5; Q8VXU7;
DT 26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 25-MAY-2022, entry version 130.
DE RecName: Full=Probable plastid-lipid-associated protein 2, chloroplastic;
DE Short=AtPap2;
DE AltName: Full=Fibrillin-1b;
DE Flags: Precursor;
GN Name=PAP2; Synonyms=FBN1b, FIB1b; OrderedLocusNames=At4g22240;
GN ORFNames=T10I14.70;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION [LARGE SCALE
RP ANALYSIS].
RC STRAIN=cv. Columbia;
RX PubMed=16461379; DOI=10.1104/pp.105.076083;
RA Ytterberg A.J., Peltier J.-B., van Wijk K.J.;
RT "Protein profiling of plastoglobules in chloroplasts and chromoplasts. A
RT surprising site for differential accumulation of metabolic enzymes.";
RL Plant Physiol. 140:984-997(2006).
RN [7]
RP FUNCTION.
RX PubMed=19906042; DOI=10.1111/j.1365-313x.2009.04067.x;
RA Youssef A., Laizet Y., Block M.A., Marechal E., Alcaraz J.P., Larson T.R.,
RA Pontier D., Gaffe J., Kuntz M.;
RT "Plant lipid-associated fibrillin proteins condition jasmonate production
RT under photosynthetic stress.";
RL Plant J. 61:436-445(2010).
RN [8]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=21571574; DOI=10.1016/j.tplants.2011.03.014;
RA Singh D.K., McNellis T.W.;
RT "Fibrillin protein function: the tip of the iceberg?";
RL Trends Plant Sci. 16:432-441(2011).
RN [9]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION [LARGE SCALE
RP ANALYSIS].
RC STRAIN=cv. Columbia;
RX PubMed=22274653; DOI=10.1104/pp.111.193144;
RA Lundquist P.K., Poliakov A., Bhuiyan N.H., Zybailov B., Sun Q.,
RA van Wijk K.J.;
RT "The functional network of the Arabidopsis plastoglobule proteome based on
RT quantitative proteomics and genome-wide coexpression analysis.";
RL Plant Physiol. 158:1172-1192(2012).
CC -!- FUNCTION: Probably involved in light/cold stress-related jasmonate (JA)
CC biosynthesis. {ECO:0000269|PubMed:19906042}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast, plastoglobule
CC {ECO:0000269|PubMed:16461379, ECO:0000269|PubMed:22274653}.
CC -!- MISCELLANEOUS: Simultaneous down-regulation of PAP1, PAP2 and PAP3
CC leads to impaired long-term acclimation to environmental constraint,
CC namely photooxidative stress imposed by high light combined with cold.
CC {ECO:0000305|PubMed:19906042}.
CC -!- SIMILARITY: Belongs to the PAP/fibrillin family. {ECO:0000305}.
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DR EMBL; AL021712; CAA16774.1; -; Genomic_DNA.
DR EMBL; AL161556; CAB79179.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE84581.1; -; Genomic_DNA.
DR EMBL; AY074581; AAL67120.1; -; mRNA.
DR EMBL; AY084549; AAM67287.1; -; mRNA.
DR EMBL; BT020429; AAW28556.1; -; mRNA.
DR EMBL; BT020480; AAW38981.1; -; mRNA.
DR PIR; T04905; T04905.
DR RefSeq; NP_193955.1; NM_118350.3.
DR AlphaFoldDB; O49629; -.
DR SMR; O49629; -.
DR BioGRID; 13608; 15.
DR IntAct; O49629; 14.
DR MINT; O49629; -.
DR STRING; 3702.AT4G22240.1; -.
DR iPTMnet; O49629; -.
DR PaxDb; O49629; -.
DR PRIDE; O49629; -.
DR ProteomicsDB; 226052; -.
DR EnsemblPlants; AT4G22240.1; AT4G22240.1; AT4G22240.
DR GeneID; 828319; -.
DR Gramene; AT4G22240.1; AT4G22240.1; AT4G22240.
DR KEGG; ath:AT4G22240; -.
DR Araport; AT4G22240; -.
DR TAIR; locus:2132006; AT4G22240.
DR eggNOG; ENOG502QS2T; Eukaryota.
DR HOGENOM; CLU_045041_1_0_1; -.
DR OMA; DKEDEWG; -.
DR OrthoDB; 1037321at2759; -.
DR PhylomeDB; O49629; -.
DR PRO; PR:O49629; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; O49629; baseline and differential.
DR Genevisible; O49629; AT.
DR GO; GO:0009507; C:chloroplast; IDA:CACAO.
DR GO; GO:0009534; C:chloroplast thylakoid; HDA:TAIR.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; HDA:TAIR.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0005739; C:mitochondrion; IDA:CACAO.
DR GO; GO:0009536; C:plastid; IDA:TAIR.
DR GO; GO:0010287; C:plastoglobule; HDA:TAIR.
DR GO; GO:0009579; C:thylakoid; HDA:TAIR.
DR GO; GO:0031977; C:thylakoid lumen; HDA:TAIR.
DR InterPro; IPR039633; PAP.
DR InterPro; IPR006843; PAP/fibrillin_dom.
DR PANTHER; PTHR31906; PTHR31906; 1.
DR Pfam; PF04755; PAP_fibrillin; 1.
PE 1: Evidence at protein level;
KW Chloroplast; Coiled coil; Phosphoprotein; Plastid; Reference proteome;
KW Transit peptide.
FT TRANSIT 1..59
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 60..310
FT /note="Probable plastid-lipid-associated protein 2,
FT chloroplastic"
FT /id="PRO_0000023209"
FT COILED 65..94
FT /evidence="ECO:0000255"
FT MOD_RES 61
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:O81439"
FT CONFLICT 11
FT /note="S -> R (in Ref. 4; AAM67287)"
FT /evidence="ECO:0000305"
FT CONFLICT 41
FT /note="P -> L (in Ref. 3; AAL67120)"
FT /evidence="ECO:0000305"
FT CONFLICT 142
FT /note="Y -> C (in Ref. 4; AAM67287)"
FT /evidence="ECO:0000305"
FT CONFLICT 268
FT /note="S -> F (in Ref. 3; AAL67120)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 310 AA; 33655 MW; 9D0A41A7DA0AA86A CRC64;
MATVQLSTQF SCQTRVSISP NSKSISKPPF LVPVTSIIHR PMISTGGIAV SPRRVFKVRA
TDTGEIGSAL LAAEEAIEDV EETERLKRSL VDSLYGTDRG LSASSETRAE IGDLITQLES
KNPTPAPTEA LFLLNGKWIL AYTSFVNLFP LLSRGIVPLI KVDEISQTID SDNFTVQNSV
RFAGPLGTNS ISTNAKFEIR SPKRVQIKFE QGVIGTPQLT DSIEIPEYVE VLGQKIDLNP
IRGLLTSVQD TASSVARTIS SQPPLKFSLP ADNAQSWLLT TYLDKDIRIS RGDGGSVFVL
IKEGSPLLNP
