ID   PAPA5_CARPA             Reviewed;          96 AA.
AC   P05993;
DT   01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1988, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Cysteine proteinase;
DE            EC=3.4.22.-;
DE   AltName: Full=Clone PLBPC13;
DE   Flags: Fragment;
OS   Carica papaya (Papaya).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Caricaceae; Carica.
OX   NCBI_TaxID=3649;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=3541893; DOI=10.1042/bj2370105;
RA   McKee R.A., Adams S., Matthews J.A., Smith C.J., Smith H.;
RT   "Molecular cloning of two cysteine proteinases from paw-paw (Carica
RT   papaya).";
RL   Biochem. J. 237:105-110(1986).
CC   -!- SIMILARITY: Belongs to the peptidase C1 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU10088, ECO:0000255|PROSITE-ProRule:PRU10089,
CC       ECO:0000255|PROSITE-ProRule:PRU10090}.
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DR   EMBL; X03971; CAA27609.1; -; mRNA.
DR   PIR; B26074; B26074.
DR   AlphaFoldDB; P05993; -.
DR   SMR; P05993; -.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR025661; Pept_asp_AS.
DR   InterPro; IPR025660; Pept_his_AS.
DR   InterPro; IPR000668; Peptidase_C1A_C.
DR   Pfam; PF00112; Peptidase_C1; 1.
DR   SUPFAM; SSF54001; SSF54001; 1.
DR   PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR   PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Protease; Thiol protease.
FT   CHAIN           <1..96
FT                   /note="Cysteine proteinase"
FT                   /id="PRO_0000050563"
FT   ACT_SITE        31
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        58
FT                   /evidence="ECO:0000250"
FT   NON_TER         1
SQ   SEQUENCE   96 AA;  10474 MW;  A0EE213D2540B405 CRC64;
     GPLAVAINAA YMQTYIGGVS CPYICSRRLN HGVLLVGYGS AGYAPIRLKE KPYWVIKNSW
     GENWGENGYY KICRGRNICG VDSMVSTVAA VHTTSQ