ID   PAPI_ECOLX              Reviewed;          77 AA.
AC   P04743;
DT   13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
DT   13-AUG-1987, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Major pilus subunit operon regulatory protein;
GN   Name=papI;
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 700336 / J96 / UPEC;
RX   PubMed=2868893; DOI=10.1002/j.1460-2075.1985.tb04162.x;
RA   Baga M., Goeransson M., Normark S., Uhlin B.E.;
RT   "Transcriptional activation of a pap pilus virulence operon from
RT   uropathogenic Escherichia coli.";
RL   EMBO J. 4:3887-3893(1985).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 700336 / J96 / UPEC;
RX   PubMed=1357526; DOI=10.1111/j.1365-2958.1992.tb01399.x;
RA   Marklund B.-I., Tennent J.M., Garcia E., Hamers A., Baga M., Lindberg F.,
RA   Gaastra W., Normark S.;
RT   "Horizontal gene transfer of the Escherichia coli pap and prs pili operons
RT   as a mechanism for the development of tissue-specific adhesive
RT   properties.";
RL   Mol. Microbiol. 6:2225-2242(1992).
CC   -!- FUNCTION: Plays a role in the inhibition of methylation at the GATC1028
CC       site located in the regulatory region upstream of the pabA promoter.
CC       May, in conjunction with the Mbf (methylation blocking factor),
CC       inhibits deoxyadenosine methylase from methylating the GATC1028 site.
CC   -!- SIMILARITY: To E.coli AfaF and DaaF. {ECO:0000305}.
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DR   EMBL; X03391; CAA27124.1; -; Genomic_DNA.
DR   EMBL; X61239; CAA43560.1; -; Genomic_DNA.
DR   PIR; A25121; RGECPI.
DR   RefSeq; WP_000006209.1; NZ_WIKQ01000028.1.
DR   AlphaFoldDB; P04743; -.
DR   SMR; P04743; -.
DR   PATRIC; fig|562.10483.peg.2953; -.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR006793; FaeA.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF04703; FaeA; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   4: Predicted;
KW   Activator; Fimbrium biogenesis; Transcription; Transcription regulation.
FT   CHAIN           1..77
FT                   /note="Major pilus subunit operon regulatory protein"
FT                   /id="PRO_0000058231"
SQ   SEQUENCE   77 AA;  8855 MW;  F4EE9C165A2C25B3 CRC64;
     MSEYMKNEIL EFLNRHNGGK TAEIAEALAV TDYQARYYLL LLEKEGMVQR SPLRRGMATY
     WFLKGEMQAG QNCSSTT