ID   PAP_GAHVM               Reviewed;         369 AA.
AC   Q77MR9;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   13-OCT-2009, sequence version 1.
DT   23-FEB-2022, entry version 33.
DE   RecName: Full=DNA polymerase processivity factor;
DE   AltName: Full=DNA-binding protein UL42;
DE   AltName: Full=Polymerase accessory protein;
DE            Short=PAP;
GN   Name=MDV055;
OS   Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's
OS   disease herpesvirus type 1).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Mardivirus.
OX   NCBI_TaxID=10389;
OH   NCBI_TaxID=9031; Gallus gallus (Chicken).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10933706; DOI=10.1128/jvi.74.17.7980-7988.2000;
RA   Tulman E.R., Afonso C.L., Lu Z., Zsak L., Rock D.L., Kutish G.F.;
RT   "The genome of a very virulent Marek's disease virus.";
RL   J. Virol. 74:7980-7988(2000).
CC   -!- FUNCTION: Plays an essential role in viral DNA replication by acting as
CC       the polymerase accessory subunit. Associates with the viral polymerase
CC       to increase its processivity and forms high-affinity direct
CC       interactions with DNA. Facilitates the origin-binding protein UL9
CC       loading onto DNA thus increasing its ability to assemble into a
CC       functional complex capable of unwinding duplex DNA (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with the DNA polymerase catalytic subunit. Interacts
CC       with the origin-binding protein (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the herpesviridae DNA polymerase processivity
CC       factor family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF243438; AAG14235.1; -; Genomic_DNA.
DR   RefSeq; YP_001033971.1; NC_002229.3.
DR   SMR; Q77MR9; -.
DR   PRIDE; Q77MR9; -.
DR   GeneID; 4811516; -.
DR   KEGG; vg:4811516; -.
DR   Proteomes; UP000008072; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   InterPro; IPR003202; Herpes_UL42.
DR   Pfam; PF02282; Herpes_UL42; 2.
PE   3: Inferred from homology;
KW   DNA replication; DNA-binding; Host nucleus; Reference proteome.
FT   CHAIN           1..369
FT                   /note="DNA polymerase processivity factor"
FT                   /id="PRO_0000406522"
FT   REGION          345..369
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   369 AA;  40226 MW;  193FCECA2142A8E0 CRC64;
     MAGITMGSEH MYDDTTFPTN DPESSWKIVL AGEKFMTASA ALKTIVGCVK NPLITFSDDG
     LMIQGTVCGQ RMFVPIDCTS FSEYEWRGPT AIFLALTDSR RTLLDAFKCD KKKVVEVCFT
     FRGEPPCRHL TQTVTYANDG CSFSSTIVKY ELWSASIICP QKTPDATFSL NKQQLSKILT
     VAAKVQHEEL IFALKAEGGF YAGTICDVIS FDIDGSAMVQ YPYNATSHAS SALIVACGKK
     KTNKSIAVTA YGSGKPFCLA LEDTNAFRNV VQKIKTGAAG ADLGFYTTCD PPMLCVRPHV
     FGSPTAFLFC NSDCMSIYEL EEVSAVSGAI KSKRISEYFP KVSNIGSRKR GPSSPPFERE
     GKLAKVINQ