ID   PAR1_TRYBB              Reviewed;         143 AA.
AC   P08469;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1988, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Procyclic form-specific polypeptide B1-alpha;
DE   AltName: Full=PARP;
DE   AltName: Full=Procyclin B1-alpha;
DE   Flags: Precursor;
OS   Trypanosoma brucei brucei.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX   NCBI_TaxID=5702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Treu 667;
RX   PubMed=3670296; DOI=10.1128/mcb.7.8.2838-2844.1987;
RA   Mowatt M.R., Clayton C.E.;
RT   "Developmental regulation of a novel repetitive protein of Trypanosoma
RT   brucei.";
RL   Mol. Cell. Biol. 7:2838-2844(1987).
CC   -!- FUNCTION: Major surface antigen of procyclic forms.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor.
CC   -!- DEVELOPMENTAL STAGE: Expressed only at a certain stage during
CC       differentiation in the insect vector.
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DR   EMBL; M17027; AAA30222.1; -; mRNA.
DR   PIR; A26918; A26918.
DR   AlphaFoldDB; P08469; -.
DR   SMR; P08469; -.
DR   GO; GO:0031225; C:anchored component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008882; Trypano_PARP.
DR   Pfam; PF05887; Trypan_PARP; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Glycoprotein; GPI-anchor; Lipoprotein; Membrane; Repeat;
KW   Signal.
FT   SIGNAL          1..27
FT   CHAIN           28..121
FT                   /note="Procyclic form-specific polypeptide B1-alpha"
FT                   /id="PRO_0000022009"
FT   PROPEP          122..143
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000022010"
FT   REPEAT          59..60
FT                   /note="1; approximate"
FT   REPEAT          61..62
FT                   /note="2; approximate"
FT   REPEAT          63..64
FT                   /note="3"
FT   REPEAT          65..66
FT                   /note="4"
FT   REPEAT          67..68
FT                   /note="5"
FT   REPEAT          69..70
FT                   /note="6"
FT   REPEAT          71..72
FT                   /note="7"
FT   REPEAT          73..74
FT                   /note="8"
FT   REPEAT          75..76
FT                   /note="9"
FT   REPEAT          77..78
FT                   /note="10"
FT   REPEAT          79..80
FT                   /note="11"
FT   REPEAT          81..82
FT                   /note="12"
FT   REPEAT          83..84
FT                   /note="13"
FT   REPEAT          85..86
FT                   /note="14"
FT   REPEAT          87..88
FT                   /note="15"
FT   REPEAT          89..90
FT                   /note="16"
FT   REPEAT          91..92
FT                   /note="17"
FT   REPEAT          93..94
FT                   /note="18"
FT   REPEAT          95..96
FT                   /note="19"
FT   REPEAT          97..98
FT                   /note="20"
FT   REPEAT          99..100
FT                   /note="21"
FT   REPEAT          101..102
FT                   /note="22"
FT   REPEAT          103..104
FT                   /note="23"
FT   REPEAT          105..106
FT                   /note="24"
FT   REPEAT          107..108
FT                   /note="25"
FT   REPEAT          109..110
FT                   /note="26"
FT   REPEAT          111..112
FT                   /note="27"
FT   REPEAT          113..114
FT                   /note="28"
FT   REPEAT          115..116
FT                   /note="29"
FT   REPEAT          117..118
FT                   /note="30"
FT   REPEAT          119..120
FT                   /note="31"
FT   REGION          28..125
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          59..120
FT                   /note="31 X 2 approximate tandem repeats of E-P"
FT   COMPBIAS        34..52
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        58..116
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           121
FT                   /note="GPI-anchor amidated glycine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        56
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   143 AA;  14881 MW;  E760F52DD46D2E54 CRC64;
     MAPRSLYLLA VLLFSANLFA GVGFAAAAEG PEDKGLTKGG KGKGEKGTKV GADDTNGTDP
     DPEPEPEPEP EPEPEPEPEP EPEPEPEPEP EPEPEPEPEP EPEPEPEPEP EPEPEPEPEP
     GAATLKSVAL PFAIAAAALV AAF