PARA_CAUVN
ID PARA_CAUVN Reviewed; 267 AA.
AC B8GW31; O05189;
DT 16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT 03-MAR-2009, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=Chromosome partitioning protein ParA;
GN Name=parA; OrderedLocusNames=CCNA_03869;
OS Caulobacter vibrioides (strain NA1000 / CB15N) (Caulobacter crescentus).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=565050;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9054507; DOI=10.1016/s0092-8674(00)81910-8;
RA Mohl D.A., Gober J.W.;
RT "Cell cycle-dependent polar localization of chromosome partitioning
RT proteins in Caulobacter crescentus.";
RL Cell 88:675-684(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA1000 / CB15N;
RX PubMed=20472802; DOI=10.1128/jb.00255-10;
RA Marks M.E., Castro-Rojas C.M., Teiling C., Du L., Kapatral V.,
RA Walunas T.L., Crosson S.;
RT "The genetic basis of laboratory adaptation in Caulobacter crescentus.";
RL J. Bacteriol. 192:3678-3688(2010).
CC -!- FUNCTION: Involved in chromosome partition. Localize to both poles of
CC the predivisional cell following completion of DNA replication.
CC -!- INTERACTION:
CC B8GW31; A0A0H3C899: tipN; NbExp=3; IntAct=EBI-8183380, EBI-6468999;
CC -!- SIMILARITY: Belongs to the ParA family. {ECO:0000305}.
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DR EMBL; U87804; AAB51267.1; -; Genomic_DNA.
DR EMBL; CP001340; ACL97334.1; -; Genomic_DNA.
DR RefSeq; WP_010921580.1; NC_011916.1.
DR RefSeq; YP_002519242.1; NC_011916.1.
DR AlphaFoldDB; B8GW31; -.
DR SMR; B8GW31; -.
DR IntAct; B8GW31; 2.
DR MINT; B8GW31; -.
DR PRIDE; B8GW31; -.
DR EnsemblBacteria; ACL97334; ACL97334; CCNA_03869.
DR GeneID; 7332717; -.
DR KEGG; ccs:CCNA_03869; -.
DR PATRIC; fig|565050.3.peg.3774; -.
DR HOGENOM; CLU_037612_1_4_5; -.
DR OMA; VQCEYFA; -.
DR OrthoDB; 729012at2; -.
DR PhylomeDB; B8GW31; -.
DR Proteomes; UP000001364; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR025669; AAA_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF13614; AAA_31; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 1: Evidence at protein level;
KW ATP-binding; Chromosome partition; Nucleotide-binding; Reference proteome.
FT CHAIN 1..267
FT /note="Chromosome partitioning protein ParA"
FT /id="PRO_0000378300"
FT BINDING 14..21
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
FT CONFLICT 31..34
FT /note="LAAC -> WAL (in Ref. 1; AAB51267)"
FT /evidence="ECO:0000305"
FT CONFLICT 175..176
FT /note="RG -> AR (in Ref. 1; AAB51267)"
FT /evidence="ECO:0000305"
FT CONFLICT 191
FT /note="M -> I (in Ref. 1; AAB51267)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 267 AA; 28870 MW; 6573A4D495A7007C CRC64;
MSANPLRVLA IANQKGGVGK TTTAINLGTA LAACGERVLL IDADPQGNCS TGLGIGRTQR
RTTLYDVLMG EAPVVDAAVK TELPGLDVIP ADADLSGVEI ELGQTARRSY RLRDALEAIR
ANGPYTYVLI DCPPSLNVLT VNAMTAADAV FVPLQCEFFA LEGLTQLMRT IERVRGSLNP
RLEIQGVVLT MYDRRNSLSE QVAKDVRAHF GDKVYDAVIP RNVRVSEAPS FGKPVLLYDL
KCAGSQAYLK LAREVISRER DRQAKAA