PARA_THET2
ID PARA_THET2 Reviewed; 322 AA.
AC Q746H1;
DT 26-JUN-2013, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Probable plasmid-partitioning protein ParA;
GN Name=parA; OrderedLocusNames=TT_P0084;
OS Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27).
OG Plasmid pTT27.
OC Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=262724;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-163 / DSM 7039 / HB27;
RX PubMed=15064768; DOI=10.1038/nbt956;
RA Henne A., Brueggemann H., Raasch C., Wiezer A., Hartsch T., Liesegang H.,
RA Johann A., Lienard T., Gohl O., Martinez-Arias R., Jacobi C.,
RA Starkuviene V., Schlenczeck S., Dencker S., Huber R., Klenk H.-P.,
RA Kramer W., Merkl R., Gottschalk G., Fritz H.-J.;
RT "The genome sequence of the extreme thermophile Thermus thermophilus.";
RL Nat. Biotechnol. 22:547-553(2004).
CC -!- FUNCTION: Probably involved in plasmid DNA partitioning. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ParA family. {ECO:0000305}.
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DR EMBL; AE017222; AAS82414.1; -; Genomic_DNA.
DR RefSeq; WP_011174477.1; NC_005838.1.
DR AlphaFoldDB; Q746H1; -.
DR SMR; Q746H1; -.
DR STRING; 262724.TT_P0084; -.
DR EnsemblBacteria; AAS82414; AAS82414; TT_P0084.
DR KEGG; tth:TT_P0084; -.
DR eggNOG; COG1192; Bacteria.
DR HOGENOM; CLU_037612_1_2_0; -.
DR OMA; PRRLSEW; -.
DR OrthoDB; 729012at2; -.
DR Proteomes; UP000000592; Plasmid pTT27.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR025669; AAA_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF13614; AAA_31; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 3: Inferred from homology;
KW ATP-binding; Chromosome partition; Nucleotide-binding; Plasmid.
FT CHAIN 1..322
FT /note="Probable plasmid-partitioning protein ParA"
FT /id="PRO_0000422777"
FT BINDING 60..67
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 322 AA; 35951 MW; 72F0EFBC142501C4 CRC64;
MKQGELVPVS EMARRLGVTR ERVRQMILEG KLEGVRLGRY WYVREREGGR LRRVYTFFTH
AGGAGKTSLA RDLGFELARR GFRVLLVDTD PQANLTSWLG VREVAPEETL LHLVDTGQLP
TPRRLSEWGL DLIPASLDLA RVEVRLMQRP LSTLLLRTAL RKTEGYDFVL IDSLPSLGHL
AALGALAGDG LLVPVETSVK GVEALVGVME AAQEYREALE QVDPRVPRSF VRLFIPTKFD
ARTLGDNRVL EKIAGLEDLA PVASPIAYRP GPHRRATERA VPLQLVGDRQ AREEVERLTE
EFLQRVVAQD AAREGVLEEV AE