ID   PARB_HELPY              Reviewed;         290 AA.
AC   O25758;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Probable chromosome-partitioning protein ParB;
GN   Name=parB; OrderedLocusNames=HP_1138;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
CC   -!- FUNCTION: Involved in chromosome partition. Localize to both poles of
CC       the predivisional cell following completion of DNA replication. Binds
CC       to the DNA origin of replication (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ParB family. {ECO:0000305}.
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DR   EMBL; AE000511; AAD08184.1; -; Genomic_DNA.
DR   PIR; B64662; B64662.
DR   RefSeq; NP_207929.1; NC_000915.1.
DR   RefSeq; WP_001107421.1; NC_018939.1.
DR   PDB; 4UMK; X-ray; 3.10 A; A/B/C/D=1-240.
DR   PDBsum; 4UMK; -.
DR   AlphaFoldDB; O25758; -.
DR   SMR; O25758; -.
DR   DIP; DIP-3152N; -.
DR   IntAct; O25758; 4.
DR   MINT; O25758; -.
DR   STRING; 85962.C694_05870; -.
DR   PaxDb; O25758; -.
DR   EnsemblBacteria; AAD08184; AAD08184; HP_1138.
DR   KEGG; hpy:HP_1138; -.
DR   PATRIC; fig|85962.47.peg.1220; -.
DR   eggNOG; COG1475; Bacteria.
DR   OMA; IALSYQR; -.
DR   PhylomeDB; O25758; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0005694; C:chromosome; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IBA:GO_Central.
DR   GO; GO:0045881; P:positive regulation of sporulation resulting in formation of a cellular spore; IBA:GO_Central.
DR   InterPro; IPR041468; HTH_ParB/Spo0J.
DR   InterPro; IPR004437; ParB/RepB/Spo0J.
DR   InterPro; IPR003115; ParB/Sulfiredoxin_dom.
DR   InterPro; IPR036086; ParB/Sulfiredoxin_sf.
DR   Pfam; PF17762; HTH_ParB; 1.
DR   Pfam; PF02195; ParBc; 1.
DR   SMART; SM00470; ParB; 1.
DR   SUPFAM; SSF110849; SSF110849; 1.
DR   TIGRFAMs; TIGR00180; parB_part; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Chromosome partition; DNA-binding; Reference proteome.
FT   CHAIN           1..290
FT                   /note="Probable chromosome-partitioning protein ParB"
FT                   /id="PRO_0000178682"
FT   HELIX           37..40
FT                   /evidence="ECO:0007829|PDB:4UMK"
FT   HELIX           56..64
FT                   /evidence="ECO:0007829|PDB:4UMK"
FT   STRAND          68..71
FT                   /evidence="ECO:0007829|PDB:4UMK"
FT   STRAND          74..77
FT                   /evidence="ECO:0007829|PDB:4UMK"
FT   STRAND          82..86
FT                   /evidence="ECO:0007829|PDB:4UMK"
FT   HELIX           88..96
FT                   /evidence="ECO:0007829|PDB:4UMK"
FT   STRAND          107..110
FT                   /evidence="ECO:0007829|PDB:4UMK"
FT   HELIX           111..122
FT                   /evidence="ECO:0007829|PDB:4UMK"
FT   HELIX           130..142
FT                   /evidence="ECO:0007829|PDB:4UMK"
FT   HELIX           148..155
FT                   /evidence="ECO:0007829|PDB:4UMK"
FT   HELIX           159..167
FT                   /evidence="ECO:0007829|PDB:4UMK"
FT   HELIX           168..170
FT                   /evidence="ECO:0007829|PDB:4UMK"
FT   HELIX           173..180
FT                   /evidence="ECO:0007829|PDB:4UMK"
FT   HELIX           186..189
FT                   /evidence="ECO:0007829|PDB:4UMK"
FT   HELIX           190..192
FT                   /evidence="ECO:0007829|PDB:4UMK"
FT   HELIX           197..210
FT                   /evidence="ECO:0007829|PDB:4UMK"
FT   HELIX           214..222
FT                   /evidence="ECO:0007829|PDB:4UMK"
SQ   SEQUENCE   290 AA;  33166 MW;  E12FE4F5E20826B8 CRC64;
     MAKNKVLGRG LADIFPEINE VYEQGLYERA NRVVELGIDE VMPNPYQPRK VFSEDSLEEL
     AQSIKEHGLL QPVLVVSENG RYHLIAGERR LRASKLAKMP TIKAIVVDIE QEKMREVALI
     ENIQREDLNP LELARSYKEL LESYQMTQEE LSKIVKKSRA HVANIMRLLT LSSKVQNALL
     EEKITSGHAK VLVGLDGEKQ ELILNSIIGQ KLSVRQTEDL ARDFKINANF DNKKHGFKQT
     QTLIAGDELE RLNQSLWDHY KLKAALKGNK IVLRCYENSL LEAFMKKMMS