PARB_MYCBO
ID PARB_MYCBO Reviewed; 344 AA.
AC P0A5R3; A0A1R3Y5M4; O53595; O53596; X2BQ08;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 79.
DE RecName: Full=Probable chromosome-partitioning protein ParB;
GN Name=parB; OrderedLocusNames=BQ2027_MB3948C;
OS Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=233413;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT "The complete genome sequence of Mycobacterium bovis.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA Robbe-Austerman S., Gordon S.V.;
RT "Updated reference genome sequence and annotation of Mycobacterium bovis
RT AF2122/97.";
RL Genome Announc. 5:E00157-E00157(2017).
CC -!- FUNCTION: Involved in chromosome partition. Localize to both poles of
CC the predivisional cell following completion of DNA replication. Binds
CC to the DNA origin of replication (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ParB family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LT708304; SIU02579.1; -; Genomic_DNA.
DR RefSeq; NP_857583.1; NC_002945.3.
DR RefSeq; WP_003400175.1; NC_002945.4.
DR AlphaFoldDB; P0A5R3; -.
DR SMR; P0A5R3; -.
DR PRIDE; P0A5R3; -.
DR EnsemblBacteria; SIU02579; SIU02579; BQ2027_MB3948C.
DR PATRIC; fig|233413.5.peg.4326; -.
DR OMA; IALSYQR; -.
DR Proteomes; UP000001419; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR InterPro; IPR041468; HTH_ParB/Spo0J.
DR InterPro; IPR004437; ParB/RepB/Spo0J.
DR InterPro; IPR003115; ParB/Sulfiredoxin_dom.
DR InterPro; IPR036086; ParB/Sulfiredoxin_sf.
DR Pfam; PF17762; HTH_ParB; 1.
DR Pfam; PF02195; ParBc; 1.
DR SMART; SM00470; ParB; 1.
DR SUPFAM; SSF110849; SSF110849; 1.
DR TIGRFAMs; TIGR00180; parB_part; 1.
PE 3: Inferred from homology;
KW Chromosome partition; DNA-binding.
FT CHAIN 1..344
FT /note="Probable chromosome-partitioning protein ParB"
FT /id="PRO_0000178686"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 259..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 344 AA; 37018 MW; 80EA58A7ED27DEBD CRC64;
MTQPSRRKGG LGRGLAALIP TGPADGESGP PTLGPRMGSA TADVVIGGPV PDTSVMGAIY
REIPPSAIEA NPRQPRQVFD EEALAELVHS IREFGLLQPI VVRSLAGSQT GVRYQIVMGE
RRWRAAQEAG LATIPAIVRE TGDDNLLRDA LLENIHRVQL NPLEEAAAYQ QLLDEFGVTH
DELAARIGRS RPLITNMIRL LKLPIPVQRR VAAGVLSAGH ARALLSLEAG PEAQEELASR
IVAEGLSVRA TEETVTLANH EANRQAHHSD ATTPAPPRRK PIQMPGLQDV AERLSTTFDT
RVTVSLGKRK GKIVVEFGSV DDLARIVGLM TTDGRDKGLH RDAL