ID   PARB_MYCLE              Reviewed;         333 AA.
AC   Q50201;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Probable chromosome-partitioning protein ParB;
GN   Name=parB; OrderedLocusNames=ML2706;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8969512; DOI=10.1099/13500872-142-11-3147;
RA   Fsihi H., de Rossi E., Salazar L., Cantoni R., Labo M., Riccardi G.,
RA   Takiff H.E., Eiglmeier K., Bergh S., Cole S.T.;
RT   "Gene arrangement and organization in an approximately 76 kb fragment
RT   encompassing the oriC region of the chromosome of Mycobacterium leprae.";
RL   Microbiology 142:3147-3161(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- FUNCTION: Involved in chromosome partition. Localize to both poles of
CC       the predivisional cell following completion of DNA replication. Binds
CC       to the DNA origin of replication (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ParB family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAC32238.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; L39923; AAB53134.1; -; Genomic_DNA.
DR   EMBL; AL583926; CAC32238.1; ALT_INIT; Genomic_DNA.
DR   PIR; H87247; H87247.
DR   RefSeq; WP_041323610.1; NC_002677.1.
DR   AlphaFoldDB; Q50201; -.
DR   SMR; Q50201; -.
DR   STRING; 272631.ML2706; -.
DR   EnsemblBacteria; CAC32238; CAC32238; CAC32238.
DR   KEGG; mle:ML2706; -.
DR   Leproma; ML2706; -.
DR   eggNOG; COG1475; Bacteria.
DR   HOGENOM; CLU_023853_0_0_11; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   InterPro; IPR041468; HTH_ParB/Spo0J.
DR   InterPro; IPR004437; ParB/RepB/Spo0J.
DR   InterPro; IPR003115; ParB/Sulfiredoxin_dom.
DR   InterPro; IPR036086; ParB/Sulfiredoxin_sf.
DR   Pfam; PF17762; HTH_ParB; 1.
DR   Pfam; PF02195; ParBc; 1.
DR   SMART; SM00470; ParB; 1.
DR   SUPFAM; SSF110849; SSF110849; 1.
DR   TIGRFAMs; TIGR00180; parB_part; 1.
PE   3: Inferred from homology;
KW   Chromosome partition; DNA-binding; Reference proteome.
FT   CHAIN           1..333
FT                   /note="Probable chromosome-partitioning protein ParB"
FT                   /id="PRO_0000178684"
SQ   SEQUENCE   333 AA;  36351 MW;  9AF78955A73769A2 CRC64;
     MTQSLCKKGG LGRGLASLIP TGPVDADSGP ATYGPQMGNT AADVLIGGSA QKDNAMGAVY
     REIALSDITE NPCQPRQVFD DEAMSELVHS IREFGLLQPI VVRPASGSCG DTRYQIVMGE
     RRWRAAQQAG LSFIPAIVRA TGDDSMLRDA LLENIHRVQL NPLEEAAAYQ QLLDEFEVTH
     DELASRIGRS RPLITNMIRL LKLPIPVQRR VAAGVLSAGH ARALLSLEAN PEVQEELASR
     IIAEGLSVRA TEEAVKLANH EVNRVNREVI TPVPQRRKPI CMPGLQDVAE RLSNAFDTRV
     MVSLGKRKGK IVVEFSSVDD LQRIVDVMTT YKT