ID   PARB_TREPA              Reviewed;         324 AA.
AC   O83295;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Probable chromosome-partitioning protein ParB;
GN   Name=parB; OrderedLocusNames=TP_0271;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- FUNCTION: Involved in chromosome partition. Localize to both poles of
CC       the predivisional cell following completion of DNA replication. Binds
CC       to the DNA origin of replication (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ParB family. {ECO:0000305}.
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DR   EMBL; AE000520; AAC65259.1; -; Genomic_DNA.
DR   PIR; A71346; A71346.
DR   RefSeq; WP_010881720.1; NC_021490.2.
DR   AlphaFoldDB; O83295; -.
DR   SMR; O83295; -.
DR   IntAct; O83295; 10.
DR   STRING; 243276.TPANIC_0271; -.
DR   EnsemblBacteria; AAC65259; AAC65259; TP_0271.
DR   GeneID; 57878815; -.
DR   KEGG; tpa:TP_0271; -.
DR   eggNOG; COG1475; Bacteria.
DR   HOGENOM; CLU_023853_0_0_12; -.
DR   OMA; IALSYQR; -.
DR   OrthoDB; 653368at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   InterPro; IPR041468; HTH_ParB/Spo0J.
DR   InterPro; IPR004437; ParB/RepB/Spo0J.
DR   InterPro; IPR003115; ParB/Sulfiredoxin_dom.
DR   InterPro; IPR036086; ParB/Sulfiredoxin_sf.
DR   Pfam; PF17762; HTH_ParB; 1.
DR   Pfam; PF02195; ParBc; 1.
DR   SMART; SM00470; ParB; 1.
DR   SUPFAM; SSF110849; SSF110849; 1.
DR   TIGRFAMs; TIGR00180; parB_part; 1.
PE   3: Inferred from homology;
KW   Chromosome partition; DNA-binding; Reference proteome.
FT   CHAIN           1..324
FT                   /note="Probable chromosome-partitioning protein ParB"
FT                   /id="PRO_0000178692"
FT   REGION          240..266
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        244..266
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   324 AA;  35430 MW;  DCCF790B2EB84276 CRC64;
     MGKDKLGKGI DALLQESSDR YDVRDSGGVQ TVHYLDPTLL QANPHQARRT FAQESLEELA
     ASIREHGVIQ PVLAEKNQDG SWVIIAGERR TRAAILAGLN RIPVIVRTCD HEKKLAIALI
     ENVQRENLNP LEEARAYQHI MDLGNLSHEE LAQRVGKNRS TITNALRLLK LPPEVQQSLS
     SRTLSAGHAR ALLSLTDMQL CVSVAQYVVT HALSVRAAEE CVACLNRGGS LHDYAGARAH
     TAASSPSPGG SATDITRLPP SSPSTDAQLD ARIRNADIAD IEQQLLEQLG TKVRISGNLQ
     RGRIEITYFS QAELERLYGL LKAH