ID   PARD_ECO57              Reviewed;          80 AA.
AC   P58092;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Antitoxin ParD;
GN   Name=parD; OrderedLocusNames=Z0509, ECs0461;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Antitoxin component of a type II toxin-antitoxin (TA) system.
CC       Neutralizes the effect of toxin ParE (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ParD antitoxin family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG54757.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33884.1; -; Genomic_DNA.
DR   PIR; A85537; A85537.
DR   PIR; E90686; E90686.
DR   RefSeq; NP_308488.1; NC_002695.1.
DR   RefSeq; WP_001226938.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P58092; -.
DR   SMR; P58092; -.
DR   STRING; 155864.EDL933_0476; -.
DR   EnsemblBacteria; AAG54757; AAG54757; Z0509.
DR   EnsemblBacteria; BAB33884; BAB33884; ECs_0461.
DR   GeneID; 67416517; -.
DR   GeneID; 914563; -.
DR   KEGG; ece:Z0509; -.
DR   KEGG; ecs:ECs_0461; -.
DR   PATRIC; fig|386585.9.peg.562; -.
DR   eggNOG; COG3609; Bacteria.
DR   HOGENOM; CLU_144805_2_1_6; -.
DR   OMA; RTECINS; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 6.10.10.120; -; 1.
DR   InterPro; IPR022789; ParD.
DR   InterPro; IPR038296; ParD_sf.
DR   InterPro; IPR010985; Ribbon_hlx_hlx.
DR   PANTHER; PTHR36582; PTHR36582; 1.
DR   Pfam; PF03693; ParD_antitoxin; 1.
DR   SUPFAM; SSF47598; SSF47598; 1.
DR   TIGRFAMs; TIGR02606; antidote_CC2985; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Toxin-antitoxin system.
FT   CHAIN           1..80
FT                   /note="Antitoxin ParD"
FT                   /id="PRO_0000216352"
SQ   SEQUENCE   80 AA;  8997 MW;  A875262BBDC0D4CC CRC64;
     MRKITSVSVG EQLDSFITRM VQSGRYGSAS EVMRSALRLL EQQESRDEAV RNAVIEGLES
     GESSMTLRDI AAERKQKHRV