ID   PARD_VIBCH              Reviewed;          80 AA.
AC   P58093;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Antitoxin ParD;
GN   Name=parD; OrderedLocusNames=VC_A0360.1;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
RN   [2]
RP   IDENTIFICATION.
RA   Medigue C., Bocs S.;
RL   Unpublished observations (APR-2001).
CC   -!- FUNCTION: Antitoxin component of a type II toxin-antitoxin (TA) system.
CC       Neutralizes the effect of toxin ParE (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ParD antitoxin family. {ECO:0000305}.
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DR   EMBL; AE003853; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; WP_001107719.1; NZ_LT906615.1.
DR   PDB; 7B22; X-ray; 3.08 A; A/B/C/D/E/F/G/H=1-80.
DR   PDBsum; 7B22; -.
DR   AlphaFoldDB; P58093; -.
DR   SASBDB; P58093; -.
DR   SMR; P58093; -.
DR   GeneID; 66940690; -.
DR   OMA; RHADYAK; -.
DR   Proteomes; UP000000584; Chromosome 2.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 6.10.10.120; -; 1.
DR   InterPro; IPR022789; ParD.
DR   InterPro; IPR038296; ParD_sf.
DR   InterPro; IPR010985; Ribbon_hlx_hlx.
DR   PANTHER; PTHR36582; PTHR36582; 1.
DR   Pfam; PF03693; ParD_antitoxin; 1.
DR   SUPFAM; SSF47598; SSF47598; 1.
DR   TIGRFAMs; TIGR02606; antidote_CC2985; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome; Toxin-antitoxin system.
FT   CHAIN           1..80
FT                   /note="Antitoxin ParD"
FT                   /id="PRO_0000216355"
FT   STRAND          5..7
FT                   /evidence="ECO:0007829|PDB:7B22"
FT   HELIX           11..22
FT                   /evidence="ECO:0007829|PDB:7B22"
FT   HELIX           29..48
FT                   /evidence="ECO:0007829|PDB:7B22"
SQ   SEQUENCE   80 AA;  8965 MW;  8698C6B6F19EEE03 CRC64;
     MAKNTSITLG EHFDGFITSQ IQSGRYGSAS EVIRSALRLL ENQETKLQSL RQLLIEGEQS
     GDADYDLDSF INELDSENIR