ID   PARD_YERPE              Reviewed;          80 AA.
AC   Q9ZGW3;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 2.
DT   25-MAY-2022, entry version 130.
DE   RecName: Full=Antitoxin ParD;
GN   Name=parD; OrderedLocusNames=YPCD1.09c, y5065, y0074, YP_pCD78;
OS   Yersinia pestis.
OG   Plasmid pCD1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=KIM5 / Biovar Mediaevalis;
RX   PubMed=9746557; DOI=10.1128/iai.66.10.4611-4623.1998;
RA   Perry R.D., Straley S.C., Fetherston J.D., Rose D.J., Gregor J.,
RA   Blattner F.R.;
RT   "DNA sequencing and analysis of the low-Ca2+-response plasmid pCD1 of
RT   Yersinia pestis KIM5.";
RL   Infect. Immun. 66:4611-4623(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
CC   -!- FUNCTION: Antitoxin component of a type II toxin-antitoxin (TA) system.
CC       Neutralizes the effect of toxin ParE (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ParD antitoxin family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAC69815.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC       Sequence=AAS58589.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC       Sequence=CAB54886.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AF074612; AAC69815.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AL117189; CAB54886.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE017043; AAS58589.1; ALT_INIT; Genomic_DNA.
DR   PIR; T42907; T42907.
DR   RefSeq; NP_395146.2; NC_003131.1.
DR   RefSeq; NP_857964.3; NC_004839.1.
DR   RefSeq; WP_002224342.1; NZ_WUCM01000133.1.
DR   RefSeq; WP_002229757.1; NC_004839.1.
DR   AlphaFoldDB; Q9ZGW3; -.
DR   SMR; Q9ZGW3; -.
DR   STRING; 214092.5832432; -.
DR   EnsemblBacteria; AAS58589; AAS58589; YP_pCD78.
DR   KEGG; ype:YPCD1.09c; -.
DR   KEGG; ypm:YP_pCD78; -.
DR   PATRIC; fig|214092.21.peg.10; -.
DR   eggNOG; COG3609; Bacteria.
DR   HOGENOM; CLU_144805_2_1_6; -.
DR   OMA; RHADYAK; -.
DR   PRO; PR:Q9ZGW3; -.
DR   Proteomes; UP000000815; Plasmid pCD1.
DR   Proteomes; UP000001019; Plasmid pCD1.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 6.10.10.120; -; 1.
DR   InterPro; IPR022789; ParD.
DR   InterPro; IPR038296; ParD_sf.
DR   InterPro; IPR010985; Ribbon_hlx_hlx.
DR   PANTHER; PTHR36582; PTHR36582; 1.
DR   Pfam; PF03693; ParD_antitoxin; 1.
DR   SUPFAM; SSF47598; SSF47598; 1.
DR   TIGRFAMs; TIGR02606; antidote_CC2985; 1.
PE   3: Inferred from homology;
KW   Plasmid; Reference proteome; Toxin-antitoxin system.
FT   CHAIN           1..80
FT                   /note="Antitoxin ParD"
FT                   /id="PRO_0000216358"
SQ   SEQUENCE   80 AA;  8865 MW;  57A85B6AB394CCAD CRC64;
     MAHVTSVTLG EHLTGFVGEM IQSGRYGNIS EVLRDALRLM EAREQRVQHV RDMVLAGTNV
     PVSHRLMDEI FSAAVKDTSV