ID   PARE1_MYCTO             Reviewed;          98 AA.
AC   P9WHG6; L0T873; P95255; Q7D7P6;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Toxin ParE1;
GN   Name=parE1; OrderedLocusNames=MT2008;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Toxic component of a type II toxin-antitoxin (TA) system. Its
CC       toxic effect is neutralized by coexpression with cognate antitoxin
CC       ParD1 (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RelE toxin family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK46280.1; -; Genomic_DNA.
DR   PIR; C70639; C70639.
DR   RefSeq; WP_003409896.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WHG6; -.
DR   SMR; P9WHG6; -.
DR   EnsemblBacteria; AAK46280; AAK46280; MT2008.
DR   GeneID; 45425929; -.
DR   KEGG; mtc:MT2008; -.
DR   PATRIC; fig|83331.31.peg.2164; -.
DR   HOGENOM; CLU_147162_3_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   Gene3D; 3.30.2310.20; -; 1.
DR   InterPro; IPR028344; ParE1/4.
DR   InterPro; IPR007712; RelE/ParE_toxin.
DR   InterPro; IPR035093; RelE/ParE_toxin_dom_sf.
DR   Pfam; PF05016; ParE_toxin; 1.
DR   PIRSF; PIRSF029218; ParE; 1.
PE   3: Inferred from homology;
KW   Toxin-antitoxin system.
FT   CHAIN           1..98
FT                   /note="Toxin ParE1"
FT                   /id="PRO_0000428190"
SQ   SEQUENCE   98 AA;  11301 MW;  64ED8124E1610091 CRC64;
     MSSRYLLSPA AQAHLEEIWD CTYDRWGVDQ AEQYLRELQH AIDRAAANPR IGRACDEIRP
     GYRKLSAGSH TLFYRVTGEG TIDVVRVLHQ RMDVDRNL