ID   PARE2_MYCTO             Reviewed;         105 AA.
AC   P9WHG4; L0TBG4; O06233; Q7D7G6;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 34.
DE   RecName: Full=Toxin ParE2;
GN   Name=parE2; OrderedLocusNames=MT2200;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Toxic component of a type II toxin-antitoxin (TA) system. Its
CC       toxic effect is neutralized by coexpression with cognate antitoxin
CC       ParD2 (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RelE toxin family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK46484.1; -; Genomic_DNA.
DR   PIR; B70578; B70578.
DR   RefSeq; WP_003411124.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WHG4; -.
DR   SMR; P9WHG4; -.
DR   EnsemblBacteria; AAK46484; AAK46484; MT2200.
DR   GeneID; 45426119; -.
DR   KEGG; mtc:MT2200; -.
DR   PATRIC; fig|83331.31.peg.2373; -.
DR   HOGENOM; CLU_2233587_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   Gene3D; 3.30.2310.20; -; 1.
DR   InterPro; IPR007712; RelE/ParE_toxin.
DR   InterPro; IPR035093; RelE/ParE_toxin_dom_sf.
DR   Pfam; PF05016; ParE_toxin; 1.
PE   3: Inferred from homology;
KW   Toxin-antitoxin system.
FT   CHAIN           1..105
FT                   /note="Toxin ParE2"
FT                   /id="PRO_0000428191"
SQ   SEQUENCE   105 AA;  12313 MW;  AD74A1CB49E1141A CRC64;
     MTRRLRVHNG VEDDLFEAFS YYADAAPDQI DRLYNLFVDA VTKRIPQAPN AFAPLFKHYR
     HIYLRPFRYY VAYRTTDEAI DILAVRHGME NPNAVEAEIS GRTFE