PAT13_MOUSE
ID PAT13_MOUSE Reviewed; 137 AA.
AC D3YWX3;
DT 07-APR-2021, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2013, sequence version 3.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Prostate and testis expressed protein 13 {ECO:0000303|PubMed:27098205};
DE AltName: Full=Prostate and testis expressed protein X {ECO:0000303|PubMed:21942998};
DE Flags: Precursor;
GN Name=Pate13 {ECO:0000303|PubMed:27098205};
GN Synonyms=Gm3867 {ECO:0000312|MGI:MGI:1925158},
GN Pate-X {ECO:0000303|PubMed:21942998};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000312|Proteomes:UP000000589};
RN [1] {ECO:0000312|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000312|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000305}
RP IDENTIFICATION, AND TISSUE SPECIFICITY.
RX PubMed=21942998; DOI=10.1186/1477-7827-9-128;
RA Turunen H.T., Sipilae P., Pujianto D.A., Damdimopoulos A.E., Bjoerkgren I.,
RA Huhtaniemi I., Poutanen M.;
RT "Members of the murine Pate family are predominantly expressed in the
RT epididymis in a segment-specific fashion and regulated by androgens and
RT other testicular factors.";
RL Reprod. Biol. Endocrinol. 9:128-128(2011).
RN [3] {ECO:0000305}
RP NOMENCLATURE.
RX PubMed=27098205; DOI=10.1186/s40246-016-0074-2;
RA Loughner C.L., Bruford E.A., McAndrews M.S., Delp E.E., Swamynathan S.,
RA Swamynathan S.K.;
RT "Organization, evolution and functions of the human and mouse Ly6/uPAR
RT family genes.";
RL Hum. Genomics 10:10-10(2016).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Strongly expressed in the epididymis, including the
CC initial segment, caput, corpus and cauda regions. Weakly expressed in
CC prostate. {ECO:0000269|PubMed:21942998}.
CC -!- SIMILARITY: Belongs to the PATE family. {ECO:0000305}.
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DR EMBL; AC157512; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006510783.1; XM_006510720.3.
DR AlphaFoldDB; D3YWX3; -.
DR STRING; 10090.ENSMUSP00000135716; -.
DR GlyGen; D3YWX3; 1 site.
DR PaxDb; D3YWX3; -.
DR PRIDE; D3YWX3; -.
DR ProteomicsDB; 353725; -.
DR Ensembl; ENSMUST00000176153; ENSMUSP00000135716; ENSMUSG00000078934.
DR GeneID; 77908; -.
DR CTD; 77908; -.
DR MGI; MGI:1925158; Pate13.
DR VEuPathDB; HostDB:ENSMUSG00000078934; -.
DR eggNOG; ENOG502T3XN; Eukaryota.
DR GeneTree; ENSGT00510000050363; -.
DR HOGENOM; CLU_152947_0_0_1; -.
DR InParanoid; D3YWX3; -.
DR OMA; GMKSCWK; -.
DR OrthoDB; 1461274at2759; -.
DR PhylomeDB; D3YWX3; -.
DR TreeFam; TF343311; -.
DR BioGRID-ORCS; 77908; 0 hits in 34 CRISPR screens.
DR Proteomes; UP000000589; Chromosome 9.
DR RNAct; D3YWX3; protein.
DR Bgee; ENSMUSG00000078934; Expressed in spermatid and 3 other tissues.
DR ExpressionAtlas; D3YWX3; baseline.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE 2: Evidence at transcript level;
KW Disulfide bond; Glycoprotein; Reference proteome; Secreted; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..137
FT /note="Prostate and testis expressed protein 13"
FT /evidence="ECO:0000255"
FT /id="PRO_5003053096"
FT DOMAIN 28..114
FT /note="UPAR/Ly6"
FT /evidence="ECO:0000305"
FT CARBOHYD 57
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 30..60
FT /evidence="ECO:0000255"
FT DISULFID 33..41
FT /evidence="ECO:0000255"
FT DISULFID 48..84
FT /evidence="ECO:0000255"
FT DISULFID 87..104
FT /evidence="ECO:0000255"
FT DISULFID 105..111
FT /evidence="ECO:0000255"
SQ SEQUENCE 137 AA; 16363 MW; 39725669E182ED6C CRC64;
MFQKLLLSVF IILLMDVGER VLTFNLLRHC NLCSHYDGFK CRNGMKSCWK FDLWTQNRTC
TTENYYYYDR FTGLYLFRYA KLNCKPCAPG MYQMFHDLLR ETFCCIDRNY CNDGTANLDT
SSILIEDMNQ KKELNDD