ID   PATE3_MOUSE             Reviewed;          98 AA.
AC   B3GLJ3; D8KWR6;
DT   25-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Prostate and testis expressed protein 3;
DE   AltName: Full=Epididymis-specific ESC112;
DE   AltName: Full=PATE-like protein DJ;
DE            Short=PATE-DJ;
DE   Flags: Precursor;
GN   Name=Pate3; Synonyms=Gm17365;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=BALB/cJ;
RX   PubMed=18387948; DOI=10.1074/jbc.m801454200;
RA   Levitin F., Weiss M., Hahn Y., Stern O., Papke R.L., Matusik R.,
RA   Nandana S.R., Ziv R., Pichinuk E., Salame S., Bera T., Vincent J., Lee B.,
RA   Pastan I., Wreschner D.H.;
RT   "PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that
RT   are expressed in reproductive and neuron-rich tissues and possess
RT   neuromodulatory activity.";
RL   J. Biol. Chem. 283:16928-16939(2008).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=C57BL/6J;
RA   Zhan X., Liu Q., Zhang Y.-L.;
RT   "Mouse ESC112 with single Ly-6 domain.";
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the PATE family. {ECO:0000305}.
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DR   EMBL; EU703626; ACD81925.1; -; mRNA.
DR   EMBL; EU004071; ABV64741.1; -; mRNA.
DR   CCDS; CCDS52755.1; -.
DR   RefSeq; NP_001161064.1; NM_001167592.2.
DR   AlphaFoldDB; B3GLJ3; -.
DR   SMR; B3GLJ3; -.
DR   STRING; 10090.ENSMUSP00000136668; -.
DR   PaxDb; B3GLJ3; -.
DR   PRIDE; B3GLJ3; -.
DR   ProteomicsDB; 294015; -.
DR   Antibodypedia; 71916; 62 antibodies from 13 providers.
DR   Ensembl; ENSMUST00000178236; ENSMUSP00000136668; ENSMUSG00000094995.
DR   GeneID; 100312956; -.
DR   KEGG; mmu:100312956; -.
DR   UCSC; uc012gql.1; mouse.
DR   CTD; 100169851; -.
DR   MGI; MGI:4936999; Pate3.
DR   VEuPathDB; HostDB:ENSMUSG00000094995; -.
DR   eggNOG; ENOG502TM14; Eukaryota.
DR   GeneTree; ENSGT00690000102487; -.
DR   HOGENOM; CLU_178161_0_0_1; -.
DR   InParanoid; B3GLJ3; -.
DR   OMA; YVHKCCN; -.
DR   PhylomeDB; B3GLJ3; -.
DR   BioGRID-ORCS; 100312956; 1 hit in 63 CRISPR screens.
DR   PRO; PR:B3GLJ3; -.
DR   Proteomes; UP000000589; Chromosome 9.
DR   RNAct; B3GLJ3; protein.
DR   Bgee; ENSMUSG00000094995; Expressed in secondary oocyte and 2 other tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR045860; Snake_toxin-like_sf.
DR   SUPFAM; SSF57302; SSF57302; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..98
FT                   /note="Prostate and testis expressed protein 3"
FT                   /id="PRO_0000354973"
FT   DOMAIN          21..97
FT                   /note="UPAR/Ly6"
FT                   /evidence="ECO:0000305"
FT   DISULFID        23..50
FT                   /evidence="ECO:0000255"
FT   DISULFID        26..35
FT                   /evidence="ECO:0000255"
FT   DISULFID        42..68
FT                   /evidence="ECO:0000255"
FT   DISULFID        72..88
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   98 AA;  11660 MW;  A33A3A21ABAAE9B9 CRC64;
     MNKHFLLLFS LFYFIVEATS LKCVTCHLRT QSDHCRRGFG VCLAQKHEIC MSLRIYFSGS
     LQLSYMVCQR FCKNLTYIFN NRTYTHKCCN SDFCNFRL