ID   ASP1_ORYSJ              Reviewed;         410 AA.
AC   Q0IU52; Q53NF8; Q6YNY7; Q6YNY8; Q71SA7;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Aspartic proteinase Asp1;
DE            Short=OSAP1;
DE            Short=OsAsp1;
DE            EC=3.4.23.-;
DE   AltName: Full=Nucellin-like protein;
DE   Flags: Precursor;
GN   Name=ASP1; OrderedLocusNames=Os11g0184800, LOC_Os11g08200;
GN   ORFNames=OsJ_031884;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RC   STRAIN=cv. Tainung 67;
RA   Yang Y.-Y., Yang J.-Y., Chung M.-C., Leu W.-M.;
RT   "OSAP1, encodes an aspartic protease-like protein, expresses synchronally
RT   during the degeneration of nucellus in rice.";
RL   Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG   The rice chromosomes 11 and 12 sequencing consortia;
RT   "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT   genes and recent gene duplications.";
RL   BMC Biol. 3:20-20(2005).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [5]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- SIMILARITY: Belongs to the peptidase A1 family. {ECO:0000305}.
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DR   EMBL; AF308691; AAQ14543.1; -; Genomic_DNA.
DR   EMBL; AF308692; AAQ14544.1; -; mRNA.
DR   EMBL; AC134047; AAY23267.1; -; Genomic_DNA.
DR   EMBL; DP000010; ABA91764.1; -; Genomic_DNA.
DR   EMBL; AP008217; BAF27763.1; -; Genomic_DNA.
DR   EMBL; AP014967; BAT12975.1; -; Genomic_DNA.
DR   EMBL; CM000148; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_015617283.1; XM_015761797.1.
DR   RefSeq; XP_015617284.1; XM_015761798.1.
DR   RefSeq; XP_015617285.1; XM_015761799.1.
DR   AlphaFoldDB; Q0IU52; -.
DR   SMR; Q0IU52; -.
DR   STRING; 4530.OS11T0184800-01; -.
DR   PaxDb; Q0IU52; -.
DR   PRIDE; Q0IU52; -.
DR   EnsemblPlants; Os11t0184800-01; Os11t0184800-01; Os11g0184800.
DR   GeneID; 4349962; -.
DR   Gramene; Os11t0184800-01; Os11t0184800-01; Os11g0184800.
DR   KEGG; osa:4349962; -.
DR   eggNOG; KOG1339; Eukaryota.
DR   HOGENOM; CLU_005738_3_0_1; -.
DR   InParanoid; Q0IU52; -.
DR   OMA; REHKHYS; -.
DR   OrthoDB; 753343at2759; -.
DR   Proteomes; UP000000763; Chromosome 11.
DR   Proteomes; UP000007752; Chromosome 11.
DR   Proteomes; UP000059680; Chromosome 11.
DR   ExpressionAtlas; Q0IU52; baseline and differential.
DR   Genevisible; Q0IU52; OS.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.70.10; -; 2.
DR   InterPro; IPR001461; Aspartic_peptidase_A1.
DR   InterPro; IPR001969; Aspartic_peptidase_AS.
DR   InterPro; IPR033121; PEPTIDASE_A1.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR032799; TAXi_C.
DR   InterPro; IPR032861; TAXi_N.
DR   PANTHER; PTHR13683; PTHR13683; 1.
DR   Pfam; PF14541; TAXi_C; 1.
DR   Pfam; PF14543; TAXi_N; 1.
DR   SUPFAM; SSF50630; SSF50630; 1.
DR   PROSITE; PS00141; ASP_PROTEASE; 2.
DR   PROSITE; PS51767; PEPTIDASE_A1; 1.
PE   2: Evidence at transcript level;
KW   Aspartyl protease; Hydrolase; Protease; Reference proteome; Repeat; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   PROPEP          24..46
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000025912"
FT   CHAIN           47..410
FT                   /note="Aspartic proteinase Asp1"
FT                   /id="PRO_0000025913"
FT   DOMAIN          38..392
FT                   /note="Peptidase A1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01103"
FT   ACT_SITE        56
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10094"
FT   ACT_SITE        257
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10094"
SQ   SEQUENCE   410 AA;  44722 MW;  558B0D80D821F3C6 CRC64;
     MTARLALLAS LLLLLQLVPP SSAVVLELHG NVYPIGHFFI TMNIGDPAKS YFLDIDTGST
     LTWLQCDAPC TNCNIVPHVL YKPTPKKLVT CADSLCTDLY TDLGKPKRCG SQKQCDYVIQ
     YVDSSSMGVL VIDRFSLSAS NGTNPTTIAF GCGYDQGKKN RNVPIPVDSI LGLSRGKVTL
     LSQLKSQGVI TKHVLGHCIS SKGGGFLFFG DAQVPTSGVT WTPMNREHKY YSPGHGTLHF
     DSNSKAISAA PMAVIFDSGA TYTYFAAQPY QATLSVVKST LNSECKFLTE VTEKDRALTV
     CWKGKDKIVT IDEVKKCFRS LSLEFADGDK KATLEIPPEH YLIISQEGHV CLGILDGSKE
     HLSLAGTNLI GGITMLDQMV IYDSERSLLG WVNYQCDRIP RSESAITSRL