ID   ASP1_STAA8              Reviewed;         517 AA.
AC   Q2FUW3;
DT   14-DEC-2011, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Accessory Sec system protein Asp1;
DE   AltName: Full=Accessory secretory protein Asp1;
GN   Name=asp1; OrderedLocusNames=SAOUHSC_02988;
OS   Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 8325 / PS 47;
RA   Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT   "The Staphylococcus aureus NCTC 8325 genome.";
RL   (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL   Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL   D.C. (2006).
RN   [2]
RP   FUNCTION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=ISP479C;
RX   PubMed=18621893; DOI=10.1128/jb.00300-08;
RA   Siboo I.R., Chaffin D.O., Rubens C.E., Sullam P.M.;
RT   "Characterization of the accessory Sec system of Staphylococcus aureus.";
RL   J. Bacteriol. 190:6188-6196(2008).
CC   -!- FUNCTION: Part of the accessory SecA2/SecY2 system specifically
CC       required to export SraP, a serine-rich repeat cell wall protein encoded
CC       upstream in the same operon. {ECO:0000269|PubMed:18621893}.
CC   -!- SUBUNIT: Part of the accessory SecA2/SecY2 protein translocation
CC       apparatus required to export cell wall protein SraP.
CC   -!- DISRUPTION PHENOTYPE: No effect on cell growth, significantly reduces
CC       export of the cell wall protein SraP. The small amount that is exported
CC       seems to be glycosylated normally. {ECO:0000269|PubMed:18621893}.
CC   -!- SIMILARITY: Belongs to the accessory Sec system protein Asp1 family.
CC       {ECO:0000305}.
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DR   EMBL; CP000253; ABD31975.1; -; Genomic_DNA.
DR   RefSeq; WP_000873197.1; NZ_LS483365.1.
DR   RefSeq; YP_501437.1; NC_007795.1.
DR   AlphaFoldDB; Q2FUW3; -.
DR   SMR; Q2FUW3; -.
DR   STRING; 1280.SAXN108_2923; -.
DR   PRIDE; Q2FUW3; -.
DR   EnsemblBacteria; ABD31975; ABD31975; SAOUHSC_02988.
DR   GeneID; 3921470; -.
DR   KEGG; sao:SAOUHSC_02988; -.
DR   PATRIC; fig|93061.5.peg.2695; -.
DR   eggNOG; ENOG502ZAK5; Bacteria.
DR   HOGENOM; CLU_038827_1_0_9; -.
DR   OMA; YYFIPAW; -.
DR   PRO; PR:Q2FUW3; -.
DR   Proteomes; UP000008816; Chromosome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR022372; Accessory_SS_Asp1.
DR   Pfam; PF16993; Asp1; 1.
DR   TIGRFAMs; TIGR03713; acc_sec_asp1; 1.
PE   3: Inferred from homology;
KW   Protein transport; Reference proteome; Translocation; Transport.
FT   CHAIN           1..517
FT                   /note="Accessory Sec system protein Asp1"
FT                   /id="PRO_0000414195"
SQ   SEQUENCE   517 AA;  61259 MW;  48D851FEF012287C CRC64;
     MKYFIPAWYD DQRWWQDTTV PYYQLQNKTE FDDMISLMGM HLENDLDYQL IVLNHAPNLR
     TFLHRYDLYE TKYSSVFDEI QGFSHHAPQA INYHHLKWPD DVEFVYTPYL LKCVTSEQTY
     TNIYFSQEGY SIWFEEFERD QLQRRYIFDD RGYLSAIRYF DDQGEASYQE YLTINGDCVL
     HEDLKNGRVT VSKRYQHHYQ QTEYNNMAQL IEEKFQAMIA QQIHEDDHVI VASDARHNRQ
     IANHIPAKSL SYSFFKNRNE TVSDEEYQSI VKNAHLIVDS VQLERDLISH QEKYQRENTM
     IRITPFETRQ SPNISSQLME TFIGVWIDGM SDADLQQMMQ RLVDYIAQED YYRLILLSRH
     QNDIPMWLRE CITSVNEEYQ AKQNADVNVS ALMTPEDQDD IIAVKTIHAE HDVVEALRTL
     RLVIDMSKEP DLYLQISAIS AGIPQINGQQ TDYVSDYDNG RIINTVDELD DALNYYLFYL
     KNWNYAYAYS LKLIDAYASK NIINQLDELI EGENDAT