PAU21_YEAST
ID PAU21_YEAST Reviewed; 164 AA.
AC P0CE86; D6W386; P42221; Q92395;
DT 23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 23-MAR-2010, sequence version 1.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=Seripauperin-21;
GN Name=PAU21; OrderedLocusNames=YOR394W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 90839 / S288c / YP1;
RX PubMed=7785338; DOI=10.1002/yea.320110410;
RA Pryde F.E., Huckle T.C., Louis E.J.;
RT "Sequence analysis of the right end of chromosome XV in Saccharomyces
RT cerevisiae: an insight into the structural and functional significance of
RT sub-telomeric repeat sequences.";
RL Yeast 11:371-382(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169874;
RA Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J.,
RA Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A.,
RA Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B.,
RA Dang V.-D., de Haan M., Delius H., Durand P., Fairhead C., Feldmann H.,
RA Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E.,
RA Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U.,
RA Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B.,
RA Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A.,
RA Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C.,
RA Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G.,
RA Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B.,
RA Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F.,
RA Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E.,
RA Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I.,
RA Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H.,
RA Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.";
RL Nature 387:98-102(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [5]
RP ALTERNATIVE INITIATION.
RC STRAIN=ATCC 201389 / BY4742;
RX PubMed=19762443; DOI=10.1099/mic.0.030726-0;
RA Luo Z., van Vuuren H.J.;
RT "Functional analyses of PAU genes in Saccharomyces cerevisiae.";
RL Microbiology 155:4036-4049(2009).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative initiation; Named isoforms=2;
CC Name=1;
CC IsoId=P0CE86-1; Sequence=Displayed;
CC Name=2;
CC IsoId=P0CE86-2; Sequence=VSP_038855;
CC -!- MISCELLANEOUS: [Isoform 2]: Produced by alternative initiation at Met-
CC 41 of isoform 1. Major isoform. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the SRP1/TIP1 family. Seripauperin subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC48993.1; Type=Erroneous termination; Note=Truncated C-terminus.; Evidence={ECO:0000305};
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DR EMBL; U23472; AAC48993.1; ALT_SEQ; Genomic_DNA.
DR EMBL; Z75302; CAA99726.1; -; Genomic_DNA.
DR EMBL; AY558031; AAS56357.1; -; Genomic_DNA.
DR EMBL; BK006948; DAA11152.1; -; Genomic_DNA.
DR PIR; S67307; S67307.
DR RefSeq; NP_015039.3; NM_001183814.3. [P0CE86-1]
DR RefSeq; NP_015041.1; NM_001184096.1. [P0CE86-1]
DR AlphaFoldDB; P0CE86; -.
DR BioGRID; 34774; 6.
DR BioGRID; 35933; 40.
DR STRING; 4932.YOR394W; -.
DR PaxDb; P0CE86; -.
DR EnsemblFungi; YMR325W_mRNA; YMR325W; YMR325W.
DR EnsemblFungi; YOR394W_mRNA; YOR394W; YOR394W. [P0CE86-1]
DR EnsemblFungi; YPL282C_mRNA; YPL282C; YPL282C. [P0CE86-1]
DR GeneID; 854576; -.
DR GeneID; 855847; -.
DR KEGG; sce:YOR394W; -.
DR KEGG; sce:YPL282C; -.
DR SGD; S000005921; PAU21.
DR VEuPathDB; FungiDB:YOR394W; -.
DR VEuPathDB; FungiDB:YPL282C; -.
DR eggNOG; ENOG502SR1B; Eukaryota.
DR HOGENOM; CLU_136376_0_0_1; -.
DR OMA; LKMQMAN; -.
DR BioCyc; YEAST:G3O-33853-MON; -.
DR PRO; PR:P0CE86; -.
DR Proteomes; UP000002311; Chromosome XV.
DR RNAct; P0CE86; protein.
DR GO; GO:0005829; C:cytosol; HDA:SGD.
DR GO; GO:0009277; C:fungal-type cell wall; IBA:GO_Central.
DR GO; GO:0005199; F:structural constituent of cell wall; IBA:GO_Central.
DR GO; GO:0031505; P:fungal-type cell wall organization; IBA:GO_Central.
DR InterPro; IPR000992; SRP1_TIP1.
DR Pfam; PF00660; SRP1_TIP1; 1.
DR PROSITE; PS00724; SRP1_TIP1; 1.
PE 3: Inferred from homology;
KW Alternative initiation; Reference proteome.
FT CHAIN 1..164
FT /note="Seripauperin-21"
FT /id="PRO_0000392931"
FT VAR_SEQ 1..40
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_038855"
FT CONFLICT 24..26
FT /note="HFF -> PSL (in Ref. 1; AAC48993)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 164 AA; 17714 MW; 8995A94853BDA67E CRC64;
MTNEGIGINR DTSTICLREY VFIHFFPVKL ISALTNKTNT MVKLTSIAAG VAAIAAGVAA
APATTTLSPS DERVNLVELG VYVSDIRAHL AQYYLFQAAH PTETYPVEIA EAVFNYGDFT
TMLTGIPAEQ VTRVITGVPW YSTRLRPAIS SALSKDGIYT AIPK
