PAU24_YEAST
ID PAU24_YEAST Reviewed; 120 AA.
AC P38155; D6VQU6;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1994, sequence version 1.
DT 03-AUG-2022, entry version 139.
DE RecName: Full=Seripauperin-24;
DE AltName: Full=Cell wall protein DAN3;
DE AltName: Full=Delayed anaerobic protein 3;
DE Flags: Precursor;
GN Name=PAU24; Synonyms=DAN3; OrderedLocusNames=YBR301W; ORFNames=YBR2120A;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=7483839; DOI=10.1002/yea.320110707;
RA Feuermann M., Charbonnel L., De Montigny J., Bloch J.C., Potier S.,
RA Souciet J.-L.;
RT "Sequence of a 9.8 kb segment of yeast chromosome II including the three
RT genes of the MAL3 locus and three unidentified open reading frames.";
RL Yeast 11:667-672(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=7813418; DOI=10.1002/j.1460-2075.1994.tb06923.x;
RA Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C.,
RA Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M.,
RA Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M.,
RA Cziepluch C., Demolis N., Delaveau T., Doignon F., Domdey H.,
RA Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D.,
RA Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N.,
RA Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J.,
RA Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C.,
RA Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P.,
RA Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y.,
RA Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F.,
RA Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E.,
RA Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M.,
RA Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B.,
RA Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L.,
RA Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M.,
RA Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S.,
RA Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K.,
RA Mewes H.-W., Kleine K.;
RT "Complete DNA sequence of yeast chromosome II.";
RL EMBO J. 13:5795-5809(1994).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [5]
RP INDUCTION.
RX PubMed=11292809; DOI=10.1128/jb.183.9.2881-2887.2001;
RA Abramova N.E., Sertil O., Mehta S., Lowry C.V.;
RT "Reciprocal regulation of anaerobic and aerobic cell wall mannoprotein gene
RT expression in Saccharomyces cerevisiae.";
RL J. Bacteriol. 183:2881-2887(2001).
RN [6]
RP INDUCTION.
RX PubMed=11160904; DOI=10.1093/nar/29.3.799;
RA Cohen B.D., Sertil O., Abramova N.E., Davies K.J.A., Lowry C.V.;
RT "Induction and repression of DAN1 and the family of anaerobic mannoprotein
RT genes in Saccharomyces cerevisiae occurs through a complex array of
RT regulatory sites.";
RL Nucleic Acids Res. 29:799-808(2001).
CC -!- FUNCTION: Component of the cell wall. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000250}.
CC -!- INDUCTION: Induced during anaerobic growth and completely repressed
CC during aerobic growth. {ECO:0000269|PubMed:11160904,
CC ECO:0000269|PubMed:11292809}.
CC -!- PTM: O-glycosylated. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SRP1/TIP1 family. Seripauperin subfamily.
CC {ECO:0000305}.
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DR EMBL; Z36169; CAA85266.1; -; Genomic_DNA.
DR EMBL; AY693110; AAT93129.1; -; Genomic_DNA.
DR EMBL; BK006936; DAA07416.1; -; Genomic_DNA.
DR PIR; S46185; S46185.
DR RefSeq; NP_009860.3; NM_001178649.3.
DR AlphaFoldDB; P38155; -.
DR BioGRID; 32993; 31.
DR DIP; DIP-4497N; -.
DR IntAct; P38155; 2.
DR STRING; 4932.YBR301W; -.
DR PaxDb; P38155; -.
DR EnsemblFungi; YBR301W_mRNA; YBR301W; YBR301W.
DR GeneID; 852603; -.
DR KEGG; sce:YBR301W; -.
DR SGD; S000000505; PAU24.
DR VEuPathDB; FungiDB:YBR301W; -.
DR eggNOG; ENOG502SR1B; Eukaryota.
DR GeneTree; ENSGT00940000176276; -.
DR HOGENOM; CLU_136376_0_0_1; -.
DR OMA; LETNANF; -.
DR BioCyc; YEAST:G3O-29217-MON; -.
DR PRO; PR:P38155; -.
DR Proteomes; UP000002311; Chromosome II.
DR RNAct; P38155; protein.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0009277; C:fungal-type cell wall; ISS:SGD.
DR GO; GO:0005199; F:structural constituent of cell wall; IBA:GO_Central.
DR GO; GO:0031505; P:fungal-type cell wall organization; IBA:GO_Central.
DR InterPro; IPR000992; SRP1_TIP1.
DR Pfam; PF00660; SRP1_TIP1; 1.
DR PROSITE; PS00724; SRP1_TIP1; 1.
PE 2: Evidence at transcript level;
KW Cell wall; Cell wall biogenesis/degradation; Glycoprotein;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..120
FT /note="Seripauperin-24"
FT /id="PRO_0000033242"
SQ SEQUENCE 120 AA; 12848 MW; 07DC8A8D357B90CC CRC64;
MVKLTSIAAG VAAIAATASA TTTLAQSDER VNLVELGVYV SDIRAHLAQY YSFQVAHPTE
TYPVEIAEAV FNYGDFTTML TGIAPDQVTR MITGVPWYSS RLKPAISSAL SKDGIYTIAN
