PAU3_YEAST
ID PAU3_YEAST Reviewed; 124 AA.
AC P25610; D6VRA4; Q6B1E0;
DT 01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1992, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Seripauperin-3;
GN Name=PAU3; OrderedLocusNames=YCR104W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=1574125; DOI=10.1038/357038a0;
RA Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M.,
RA Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G.,
RA Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A.,
RA Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M., Carcano C.,
RA Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M.,
RA Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C.,
RA Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F.,
RA Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C.,
RA Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E.,
RA Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P.,
RA Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J.,
RA Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P.,
RA Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M.,
RA Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P.,
RA Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G.,
RA Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E.,
RA Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F.,
RA Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L.,
RA Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J.,
RA Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M.,
RA Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A.,
RA Richterich P., Roberts A.B., Rodriguez F., Sanz E.,
RA Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J.,
RA Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I.,
RA Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M.,
RA Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M.,
RA Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D.,
RA Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K.,
RA Sgouros J.G.;
RT "The complete DNA sequence of yeast chromosome III.";
RL Nature 357:38-46(1992).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [4]
RP SIMILARITY TO SRP1/TIP1.
RX PubMed=1304897; DOI=10.1002/pro.5560011216;
RA Bork P., Ouzounis C., Sander C., Scharf M., Schneider R., Sonnhammer E.;
RT "Comprehensive sequence analysis of the 182 predicted open reading frames
RT of yeast chromosome III.";
RL Protein Sci. 1:1677-1690(1992).
RN [5]
RP GENE NAME.
RX PubMed=7926827; DOI=10.1016/0378-1119(94)90249-6;
RA Viswanathan M., Muthukumar G., Cong Y.-S., Lenard J.;
RT "Seripauperins of Saccharomyces cerevisiae: a new multigene family encoding
RT serine-poor relatives of serine-rich proteins.";
RL Gene 148:149-153(1994).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the SRP1/TIP1 family. Seripauperin subfamily.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X59720; CAA42246.1; -; Genomic_DNA.
DR EMBL; AY693140; AAT93159.1; -; Genomic_DNA.
DR EMBL; BK006937; DAA07573.1; -; Genomic_DNA.
DR PIR; S19416; S19416.
DR RefSeq; NP_010029.1; NM_001178811.1.
DR AlphaFoldDB; P25610; -.
DR SMR; P25610; -.
DR BioGRID; 31076; 33.
DR STRING; 4932.YCR104W; -.
DR PaxDb; P25610; -.
DR EnsemblFungi; YCR104W_mRNA; YCR104W; YCR104W.
DR GeneID; 850468; -.
DR KEGG; sce:YCR104W; -.
DR SGD; S000000701; PAU3.
DR VEuPathDB; FungiDB:YCR104W; -.
DR eggNOG; ENOG502SR1B; Eukaryota.
DR GeneTree; ENSGT00940000176276; -.
DR HOGENOM; CLU_136376_0_0_1; -.
DR BioCyc; YEAST:G3O-29397-MON; -.
DR PRO; PR:P25610; -.
DR Proteomes; UP000002311; Chromosome III.
DR RNAct; P25610; protein.
DR GO; GO:0009277; C:fungal-type cell wall; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005199; F:structural constituent of cell wall; IBA:GO_Central.
DR GO; GO:0031505; P:fungal-type cell wall organization; IBA:GO_Central.
DR InterPro; IPR000992; SRP1_TIP1.
DR Pfam; PF00660; SRP1_TIP1; 1.
DR PROSITE; PS00724; SRP1_TIP1; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..124
FT /note="Seripauperin-3"
FT /id="PRO_0000203780"
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 64
FT /note="T -> S (in Ref. 3; AAT93159)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 124 AA; 13187 MW; 567D09D662E8D461 CRC64;
MVKLTSIAAG VAAIAAGIAA APATTTLSPS DERVNLVELG VYVSDIRAHL AQYYLFQAAH
PTETYPVEIA EAVFNYGDFT TMLTGIPAEQ VTRVITGVPW YSTRLRPAIS SALSKDGIYT
AIPK
