ID   PAX9_CHICK              Reviewed;         339 AA.
AC   P55166;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Paired box protein Pax-9;
DE   Flags: Fragment;
GN   Name=PAX9;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8812138; DOI=10.1006/dbio.1996.0227;
RA   Mueller T.S., Ebensperger C., Neubueser A., Koseki H., Balling R.,
RA   Christ B., Wilting J.;
RT   "Expression of avian Pax1 and Pax9 is intrinsically regulated in the
RT   pharyngeal endoderm, but depends on environmental influences in the
RT   paraxial mesoderm.";
RL   Dev. Biol. 178:403-417(1996).
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X92652; CAA63343.1; -; mRNA.
DR   AlphaFoldDB; P55166; -.
DR   SMR; P55166; -.
DR   STRING; 9031.ENSGALP00000037011; -.
DR   PaxDb; P55166; -.
DR   PRIDE; P55166; -.
DR   VEuPathDB; HostDB:geneid_395740; -.
DR   eggNOG; KOG3517; Eukaryota.
DR   InParanoid; P55166; -.
DR   OrthoDB; 1339212at2759; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0048856; P:anatomical structure development; IBA:GO_Central.
DR   GO; GO:0009887; P:animal organ morphogenesis; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   CDD; cd00131; PAX; 1.
DR   Gene3D; 1.10.10.10; -; 2.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR043182; PAIRED_DNA-bd_dom.
DR   InterPro; IPR001523; Paired_dom.
DR   InterPro; IPR033204; PAX9.
DR   InterPro; IPR043565; PAX_fam.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR45636; PTHR45636; 1.
DR   PANTHER; PTHR45636:SF13; PTHR45636:SF13; 1.
DR   Pfam; PF00292; PAX; 1.
DR   PRINTS; PR00027; PAIREDBOX.
DR   SMART; SM00351; PAX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00034; PAIRED_1; 1.
DR   PROSITE; PS51057; PAIRED_2; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; DNA-binding; Nucleus; Paired box;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           <1..339
FT                   /note="Paired box protein Pax-9"
FT                   /id="PRO_0000050214"
FT   DNA_BIND        2..128
FT                   /note="Paired"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00381"
FT   REGION          5..61
FT                   /note="PAI subdomain"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00381"
FT   REGION          80..128
FT                   /note="RED subdomain"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00381"
FT   NON_TER         1
SQ   SEQUENCE   339 AA;  36214 MW;  E57764C9FCB54D6F CRC64;
     PAFGEVNQLG GVFVNGRPLP NAIRLRIVEL AQLGIRPCDI SRQLRVSHGC VSKILARYNE
     TGSILPGAIG GSKPRVTTPT VVKHIRTYKQ RDPGIFAWEI RDRLLADGVC DKYNVPSVSS
     ISRILRNKIG NLSQQGHYES YKQHQPPPQP PLPYNHIYSY PSPIAAAGAK VPTPPGVPAI
     PGTMAMPRTW PSSHSVTDIL GIRSITDQVS DTSSYPSPKV EEWSSLGRSS FPPAAQHAVN
     GLEKSSLEQE AKYSQAHNGL PAVGSFVSAP AMSPYATSAQ VSPYMPYSAA PSSYMAGHGW
     QHTAGTPLSP HGCDLPASLA FKGVQTAREG SHSVTASAL