PAX_I00A0
ID PAX_I00A0 Reviewed; 252 AA.
AC P0CK84;
DT 03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2012, sequence version 1.
DT 02-DEC-2020, entry version 24.
DE RecName: Full=Protein PA-X;
GN Name=PA;
OS Influenza A virus (strain A/Duck/Hong Kong/2986.1/2000 H5N1 genotype C).
OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC Insthoviricetes; Articulavirales; Orthomyxoviridae; Alphainfluenzavirus.
OX NCBI_TaxID=176674;
OH NCBI_TaxID=8782; Aves.
OH NCBI_TaxID=9685; Felis catus (Cat) (Felis silvestris catus).
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9691; Panthera pardus (Leopard) (Felis pardus).
OH NCBI_TaxID=9694; Panthera tigris (Tiger).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=11878904; DOI=10.1006/viro.2001.1207;
RA Guan Y., Peiris M., Kong K.F., Dyrting K.C., Ellis T.M., Sit T.,
RA Zhang L.J., Shortridge K.F.;
RT "H5N1 influenza viruses isolated from geese in Southeastern China: evidence
RT for genetic reassortment and interspecies transmission to ducks.";
RL Virology 292:16-23(2002).
CC -!- FUNCTION: May play a role in the modulation of host immune response.
CC {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Ribosomal frameshifting; Named isoforms=2;
CC Name=PA-X;
CC IsoId=P0CK84-1; Sequence=Displayed;
CC Name=PA;
CC IsoId=Q8QPG0-1; Sequence=External;
CC -!- SIMILARITY: Belongs to the influenza viruses PA-X family.
CC {ECO:0000305}.
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DR EMBL; AY059532; -; NOT_ANNOTATED_CDS; Genomic_RNA.
DR SMR; P0CK84; -.
DR Proteomes; UP000008285; Genome.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR Gene3D; 3.40.91.90; -; 1.
DR InterPro; IPR001009; PA/PA-X.
DR InterPro; IPR038372; PA/PA-X_sf.
DR Pfam; PF00603; Flu_PA; 1.
PE 3: Inferred from homology;
KW Ribosomal frameshifting.
FT CHAIN 1..252
FT /note="Protein PA-X"
FT /id="PRO_0000419367"
SQ SEQUENCE 252 AA; 29403 MW; F14B66E2BE86C89D CRC64;
MEDFVRQCFN PMIVELAEKA MKEYGEDPKI ETNKFAAICT HLEVCFMYSD FHFIDERSES
IIVESGDPNA LLKHRFEIIE GRDRTMAWTV VNSICNTTGV EKPKFLPDLY DYKENRFIEI
GVTRREVHIY YLEKANKIKS EKTHIHIFSF TGEEMATKAD YTLDEESRAR IKTRLFTIRQ
EMASRGLWDS FVNPREAKRQ LKKDLKSLEP CAGLPTKVSH RTSPALKTLE PMWMDSNRTA
ALRASFLKCQ KK