PAX_I02A0
ID PAX_I02A0 Reviewed; 252 AA.
AC P0CK69;
DT 03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2012, sequence version 1.
DT 07-OCT-2020, entry version 18.
DE RecName: Full=Protein PA-X;
GN Name=PA;
OS Influenza A virus (strain A/Chicken/Brescia/1902 H7N7).
OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC Insthoviricetes; Articulavirales; Orthomyxoviridae; Alphainfluenzavirus.
OX NCBI_TaxID=36418;
OH NCBI_TaxID=8782; Aves.
OH NCBI_TaxID=9796; Equus caballus (Horse).
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9709; Phocidae (true seals).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=16439620; DOI=10.1126/science.1121586;
RA Obenauer J.C., Denson J., Mehta P.K., Su X., Mukatira S., Finkelstein D.B.,
RA Xu X., Wang J., Ma J., Fan Y., Rakestraw K.M., Webster R.G., Hoffmann E.,
RA Krauss S., Zheng J., Zhang Z., Naeve C.W.;
RT "Large-scale sequence analysis of avian influenza isolates.";
RL Science 311:1576-1580(2006).
CC -!- FUNCTION: May play a role in the modulation of host immune response.
CC {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Ribosomal frameshifting; Named isoforms=2;
CC Name=PA-X;
CC IsoId=P0CK69-1; Sequence=Displayed;
CC Name=PA;
CC IsoId=Q0A2K9-1; Sequence=External;
CC -!- SIMILARITY: Belongs to the influenza viruses PA-X family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CY015057; -; NOT_ANNOTATED_CDS; Genomic_RNA.
DR SMR; P0CK69; -.
DR Proteomes; UP000160986; Genome.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR Gene3D; 3.40.91.90; -; 1.
DR InterPro; IPR001009; PA/PA-X.
DR InterPro; IPR038372; PA/PA-X_sf.
DR Pfam; PF00603; Flu_PA; 1.
PE 3: Inferred from homology;
KW Ribosomal frameshifting.
FT CHAIN 1..252
FT /note="Protein PA-X"
FT /id="PRO_0000419352"
SQ SEQUENCE 252 AA; 29436 MW; D7C7B4A4A522FCDA CRC64;
MEDFVRQCFN PMIVELAEKA MKEYGEDPKL ETNKFAAICT HLEVCFMYSD FHFIDERGES
IIVESSDPNA LLKHRFEIIE GRDRTMAWTV VNSICNTTGV EKPKFLPDLY DYKENRFIEV
GVTRREVHIY YLEKANKIKS EKTHIHIFSF TGEEMATKED YTLDEESRAR IKTRLYTIRQ
EMASRGLWDS FVSPREAKRQ LKKDLKSQEL CAGLPTKVSH RTSPALKTLE PMWMDSNRTA
ALRASFLKCP KK