ID   PAX_I06A0               Reviewed;         252 AA.
AC   P0DJU2;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2012, sequence version 1.
DT   02-DEC-2020, entry version 24.
DE   RecName: Full=Protein PA-X;
GN   Name=PA;
OS   Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC   Insthoviricetes; Articulavirales; Orthomyxoviridae; Alphainfluenzavirus.
OX   NCBI_TaxID=518998;
OH   NCBI_TaxID=8782; Aves.
OH   NCBI_TaxID=9606; Homo sapiens (Human).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RA   Spiro D., Halpin R., Boyne A., Bera J., Ghedin E., Hostetler J.,
RA   Fedorova N., Hine E., Overton L., Djuric K., Sarmiento M., Sitz J.,
RA   Katzel D., Manojkumar R., Devis R., Fulvini A., Silverman J., Le J.,
RA   Kilbourne E.D., Pokorny B., Bucher D., Orff E., Minieri J., Onodera S.,
RA   Huang L., Bao Y., Sanders R., Dernovoy D., Kiryutin B., Lipman D.J.,
RA   Tatusova T.;
RT   "The NIAID influenza genome sequencing project.";
RL   Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RG   The NIAID Influenza Genome Sequencing Consortium;
RL   Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in the modulation of host immune response.
CC       {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Ribosomal frameshifting; Named isoforms=2;
CC       Name=PA-X;
CC         IsoId=P0DJU2-1; Sequence=Displayed;
CC       Name=PA;
CC         IsoId=B4URE3-1; Sequence=External;
CC   -!- SIMILARITY: Belongs to the influenza viruses PA-X family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CY034129; -; NOT_ANNOTATED_CDS; Viral_cRNA.
DR   SMR; P0DJU2; -.
DR   Proteomes; UP000008081; Genome.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR   Gene3D; 3.40.91.90; -; 1.
DR   InterPro; IPR001009; PA/PA-X.
DR   InterPro; IPR038372; PA/PA-X_sf.
DR   Pfam; PF00603; Flu_PA; 1.
PE   3: Inferred from homology;
KW   Ribosomal frameshifting.
FT   CHAIN           1..252
FT                   /note="Protein PA-X"
FT                   /id="PRO_0000419405"
SQ   SEQUENCE   252 AA;  29423 MW;  568F665AAE504C4C CRC64;
     MEDFVRQCFN PMIVELAEKT MKEYGEDLKI ETNKFAAICT HLEVCFMYSD FHFINEQGES
     IIVELGDPNA LLKHRFEIIE GRDRTMAWTV VNSICNTTGA EKPKFLPDLY DYKENRFIEI
     GVTRREVHIY YLEKANKIKS EKTHIHIFSF TGEEMATKAD YTLDEESRAR IKTRLFTIRQ
     EMASRGLWDS FVSPREEKRQ LKKGLKSQEQ CASLPTKVSR RTSPALKILE PMWMDSNRTA
     TLRASCLKCP KK