PAX_I30A0
ID PAX_I30A0 Reviewed; 252 AA.
AC P0DJV0;
DT 03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2012, sequence version 1.
DT 07-OCT-2020, entry version 19.
DE RecName: Full=Protein PA-X;
GN Name=PA;
OS Influenza A virus (strain A/Swine/Iowa/15/1930 H1N1).
OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC Insthoviricetes; Articulavirales; Orthomyxoviridae; Alphainfluenzavirus.
OX NCBI_TaxID=380342;
OH NCBI_TaxID=8782; Aves.
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2800339; DOI=10.1016/0042-6822(89)90202-x;
RA Okazaki K., Kawaoka Y., Webster R.G.;
RT "Evolutionary pathways of the PA genes of influenza A viruses.";
RL Virology 172:601-608(1989).
CC -!- FUNCTION: May play a role in the modulation of host immune response.
CC {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Ribosomal frameshifting; Named isoforms=2;
CC Name=PA-X;
CC IsoId=P0DJV0-1; Sequence=Displayed;
CC Name=PA;
CC IsoId=P13175-1; Sequence=External;
CC -!- SIMILARITY: Belongs to the influenza viruses PA-X family.
CC {ECO:0000305}.
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DR EMBL; M26076; -; NOT_ANNOTATED_CDS; Genomic_RNA.
DR SMR; P0DJV0; -.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR Gene3D; 3.40.91.90; -; 1.
DR InterPro; IPR001009; PA/PA-X.
DR InterPro; IPR038372; PA/PA-X_sf.
DR Pfam; PF00603; Flu_PA; 1.
PE 3: Inferred from homology;
KW Ribosomal frameshifting.
FT CHAIN 1..252
FT /note="Protein PA-X"
FT /id="PRO_0000419413"
SQ SEQUENCE 252 AA; 29201 MW; D8A790D23E92EEF2 CRC64;
MEDFVRQCFN PMIVELAEKA MKEYGEDPRI ETNKFAAICT HMEVSFMYSD FHFINERGES
IIVESGDPNA LLKHRFEIIE GRDRAMAWTV VNSICNTTGV GKPKFLPDLY DYKEDRFIEI
GVTRREVHIY YLEKANKIKS EETHIHIFSF TGEEMATKAD YTLDEESRAR IKTRLFTIRQ
EMASRGLWDS FASPREAKRQ LKKDLKSQGQ CAGLPTKVSH RISPVLKTLG HMWMDSSRTA
TLRASFLKCP KK