ID   PAX_I33A0               Reviewed;         252 AA.
AC   P0DJW8;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2012, sequence version 1.
DT   03-AUG-2022, entry version 27.
DE   RecName: Full=Protein PA-X;
GN   Name=PA;
OS   Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus
OS   (strain A/WS/1933 H1N1)).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC   Insthoviricetes; Articulavirales; Orthomyxoviridae; Alphainfluenzavirus.
OX   NCBI_TaxID=381518;
OH   NCBI_TaxID=8782; Aves.
OH   NCBI_TaxID=9606; Homo sapiens (Human).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2308849; DOI=10.1093/nar/18.3.654;
RA   Odagiri T., Tobita K.;
RT   "Nucleotide sequence of the PA gene of influenza A/WSN/33(H1N1).";
RL   Nucleic Acids Res. 18:654-654(1990).
CC   -!- FUNCTION: May play a role in the modulation of host immune response.
CC       {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Ribosomal frameshifting; Named isoforms=2;
CC       Name=PA-X;
CC         IsoId=P0DJW8-1; Sequence=Displayed;
CC       Name=PA;
CC         IsoId=P15659-1; Sequence=External;
CC   -!- SIMILARITY: Belongs to the influenza viruses PA-X family.
CC       {ECO:0000305}.
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DR   EMBL; X17336; -; NOT_ANNOTATED_CDS; Genomic_RNA.
DR   SMR; P0DJW8; -.
DR   Proteomes; UP000000834; Genome.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR   Gene3D; 3.40.91.90; -; 1.
DR   InterPro; IPR001009; PA/PA-X.
DR   InterPro; IPR038372; PA/PA-X_sf.
DR   Pfam; PF00603; Flu_PA; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribosomal frameshifting.
FT   CHAIN           1..252
FT                   /note="Protein PA-X"
FT                   /id="PRO_0000419431"
SQ   SEQUENCE   252 AA;  29391 MW;  5FD1B070AF84B755 CRC64;
     MEDFVRQCFN PMIVELAEKA MKEYGEDLKI ETNKFAAICT HLEVCFMYSD FHFIDEQGES
     IVVELGDPNA LLKHRFEIIE GRDRTIAWTV INSICNTTGA EKPKFLPDLY DYKKNRFIEI
     GVTRREVHIY YLEKANKIKS EKTHIHIFSF TGEEMATKAD YTLDEESRAR IKTRLFTIRQ
     EMASRGLWDS FVSPREAKRQ LKKDLKSQEQ CASLPTKVSR QTSPALKILE PMWMDSNRTA
     TLRASFLKCP KK