ID   PAX_I34A0               Reviewed;         252 AA.
AC   P0CK89;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2012, sequence version 1.
DT   02-DEC-2020, entry version 20.
DE   RecName: Full=Protein PA-X;
GN   Name=PA;
OS   Influenza A virus (strain A/Fowl plague virus/Rostock/8/1934 H7N1).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC   Insthoviricetes; Articulavirales; Orthomyxoviridae; Alphainfluenzavirus.
OX   NCBI_TaxID=392810;
OH   NCBI_TaxID=8782; Aves.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=3629978; DOI=10.1016/0042-6822(87)90040-7;
RA   Robertson J.S., Newman R., Oxford J.S., Daniels R.S., Webster R.G.,
RA   Schild G.C.;
RT   "Structural changes in the haemagglutinin which accompany egg adaptation of
RT   an influenza A(H1N1) virus.";
RL   Virology 160:31-37(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RA   Robertson J.S., Elaine M., Robertson St C., Roditi I.J.;
RT   "Nucleotide sequence of RNA segment 3 of the avian influenza
RT   A/FPV/Rostock/34 and its comparison with the corresponding segment of human
RT   strains A/PR/8/34 and A/NT/60/68.";
RL   Virus Res. 1:73-79(1984).
CC   -!- FUNCTION: May play a role in the modulation of host immune response.
CC       {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Ribosomal frameshifting; Named isoforms=2;
CC       Name=PA-X;
CC         IsoId=P0CK89-1; Sequence=Displayed;
CC       Name=PA;
CC         IsoId=P12444-1; Sequence=External;
CC   -!- SIMILARITY: Belongs to the influenza viruses PA-X family.
CC       {ECO:0000305}.
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DR   EMBL; X17223; -; NOT_ANNOTATED_CDS; Genomic_RNA.
DR   EMBL; M21850; -; NOT_ANNOTATED_CDS; Genomic_RNA.
DR   SMR; P0CK89; -.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR   Gene3D; 3.40.91.90; -; 1.
DR   InterPro; IPR001009; PA/PA-X.
DR   InterPro; IPR038372; PA/PA-X_sf.
DR   Pfam; PF00603; Flu_PA; 1.
PE   3: Inferred from homology;
KW   Ribosomal frameshifting.
FT   CHAIN           1..252
FT                   /note="Protein PA-X"
FT                   /id="PRO_0000419372"
SQ   SEQUENCE   252 AA;  29402 MW;  F82A934C93ECE78B CRC64;
     MEEFVRQCFN PMIVELAEKT MKEYGEDPKI ETNKFAAICT HLEVCFMYSD FHFIDERGES
     KIVESGDPNA LLKHRFEIIE GRDRTMAWTV VNSICNTTGV EKPKFLPDLY DYKENRFIEI
     GVTRREVHIY YLEKANKIKS EKTHIHIFSF TGEEMATKAD YTLDEESRAR IKTRLFTIRQ
     EMASRGLWDS FVSPREAKRQ LKKDLKSQEP CAGLPNKVSH RTSPALKTLE PMWMDSNRTA
     ALRASFLKCP KK